ROBERT BENJAMIN STEIN
Medical Practice in San Diego, CA

License number

Pennsylvania MD028019E

Personal information

See more information about ROBERT BENJAMIN STEIN at radaris.com

Name

Address

Phone

Robert Stein, age 79

500 W Harbor Dr UNIT 917, San Diego, CA 92101

(619) 234-0299

Robert Stein

49 Cherry Ridge Ter, N Cambria, PA 15714

(814) 434-9850

Robert Stein

507 Muir Ct, Vacaville, CA 95687

(707) 447-1997

Robert Stein, age 68

514 Howard St, E Pittsburgh, PA 15112

(412) 260-0585

Robert Stein

513 W Liberty St, Allentown, PA 18102

Professional information

Non-Steroid Progesterone Receptor Agonist And Antagonist And Compounds And Methods

US Patent:

5808139, Sep 15, 1998

Filed:

Sep 8, 1994

Appl. No.:

8/303138

Inventors:

I. Charles Pathirana - San Diego CA
Christina S. Berger - San Diego CA
Robert B. Stein - San Diego CA
William Fenical - Del Mar CA
Todd K. Jones - Solana Beach CA
Lawrence G. Hamann - San Diego CA
Michael G. Johnson - San Diego CA
Luc Farmer - La Jolla CA

Assignee:

Ligand Pharmaceuticals Incorporated - San Diego CA
The Regents of the University of California - Oakland CA

International Classification:

C07C 6976

US Classification:

560138

Abstract:

Non-steroidal compounds which are high affinity, high specificity ligands for progesterone receptors are disclosed. The compounds include synthetic derivatives of cyclocymopol and its diastereomers, spectroscopically and chromatographically pure (3R)-cyclocymopol monomethyl ether, which functions as a progesterone receptor antagonist, and spectroscopically and chromatographically pure (3S)-cyclocymopol monomethyl ether, which functions as a progesterone receptor agonist. Also disclosed are methods for employing the disclosed compounds for modulating processes mediated by progesterone receptors and for treating patients requiring progesterone receptor agonist or antagonist therapy.

Use Of Selective Ligands For Treatment Of Disease States Responsive To Steroid Or Steroid-Like Retinoids

US Patent:

5668175, Sep 16, 1997

Filed:

Aug 12, 1996

Appl. No.:

8/695743

Inventors:

Ronald M. Evans - La Jolla CA
Richard A. Heyman - Encinitas CA
Christina S. Berger - San Diego CA
Robert B. Stein - San Diego CA

Assignee:

The Salk Institute for Biological Studies - La Jolla CA

International Classification:

A61K 3119, A61K 31165

US Classification:

514569

Abstract:

In accordance with the present invention, there is provided a method for the treatment of subjects afflicted with steroid or steroid-like hormone-responsive disease states. The invention method comprises administering to the subject an effective amount of a ligand which selectively interacts with the receptor subtype associated with the steroid or steroid-like hormone-responsive disease state, wherein said ligand interacts with said receptor subtype to a significantly greater extent than with other subtypes of the same receptor class.