ROBERT B MEYER, DDS, MS
Dentist at Kildaire Farm Rd, Cary, NC
License number
North Carolina 5364
Category
Dentist
Type
Orthodontics and Dentofacial Orthopedics
Address
Address
1815 Kildaire Farm Rd STE C, Cary, NC 27511
Phone
(919) 852-0009
Personal information
See more information about ROBERT B MEYER at radaris.comName
Address
Phone
521 Glenview Ave, Hendersonville, NC 28791
517 Spruce Meadows Ln, Willow Spring, NC 27592
5413 Cross Creek Rd, Wilmington, NC 28403
5012 Windcrest Way, Monroe, NC 28110
6801 Valley Dr, Raleigh, NC 27612
Organization information
See more information about ROBERT B MEYER at bizstanding.comRobert B. Meyer, DDS, MS, PA
1815 Kildaire Farm Rd Ste C, Cary, NC 27511
Doing business as:
Meyer, Robert B., DDS, MS, PA, Meyer Orthodontics
Registration:
Aug 10, 1995
Site:
Phone:
(919) 852-0009 (Phone), (919) 852-5349 (Fax)
Categories:
Orthodontists
Robert B Meyer Pa
1815 Kildaire Farm Rd STE C, Cary, NC 27518
Doing business as:
Robert B Meyer Pa - Robert B Meyer DDS
Site:
Phone:
(919) 852-0009 (Phone)
Categories:
Dentists, Orthodontics Dentists
Products:
Braces, Brace Yourself for A Fantastic Smile!, Braces for Children & Adults, ...
Payment options:
All Major Cards Accepted, American Express, Diner's Club, ...
Certifications:
Diplomate, American Board of Orthodontics
Additional:
Affordable Monthly Payment Options
ROBERT B. MEYER, D.D.S., PA
110 Widencombe Ct, Cary, NC 27513
Registration:
Aug 10, 1995
State ID:
0375268
Agent:
Robert B Meyer
Professional information
Methods For Improving Therapeutic Effectiveness Of Agents For The Treatment Of Solid Tumors And Other Disorders
US Patent:
5788958, Aug 4, 1998
Filed:
Sep 6, 1996
Appl. No.:
8/709938
Inventors:
Mark W. Dewhirst - Chapel Hill NC
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Assignee:
Duke University - Durham NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
International Classification:
A61K 3177, A61K 3816, A01N 3724, C07C20513
US Classification:
424 7838
Abstract:
The present invention is directed to the use of an inhibitor of NO activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as an antitumor therapy to reduce tumor blood flow and oxygenation. The invention is also directed to administration of a nitric oxide scavenger or a nitric oxide synthase inhibitor to enhance the effectiveness of tumor therapy with hypoxic or acidic chemotherapeutic agents or hyperthermia. The invention is also directed to the administration of a nitric oxide synthase substrate to a subject previously administered a nitric oxide synthase inhibitor, in order to selectively inhibit tumor perfusion. In a specific example, administration of cell free hemoglobin, a nitric oxide scavenger, in conjunction with mitomycin C, a hypoxic cytotoxin, results in a significant delay in tumor growth of a human tumor xenograft in a mouse compared to mitomycin C alone. In another example, the administration of an inhibitor of nitric oxide synthase followed by the administration of a substrate of the enzyme causes a specific irreversible reduction of tumor blood flow, while normal blood flow is restored.
Methods For Improving Therapeutic Effectiveness Of Agents For The Treatment Of Solid Tumors And Other Disorders
US Patent:
5554638, Sep 10, 1996
Filed:
May 20, 1994
Appl. No.:
8/246882
Inventors:
Mark W. Dewhirst - Chapel Hill NC
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Assignee:
Duke University - Durham NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
International Classification:
A61K 3122, A61K 31415
US Classification:
514398
Abstract:
The present invention is directed to the use of an inhibitor of NO activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as an antitumor therapy to reduce tumor blood flow and oxygenation. The invention is also directed to administration of a nitric oxide scavenger or a nitric oxide synthase inhibitor to enhance the effectiveness of tumor therapy with hypoxic or acidic chemotherapeutic agents or hyperthermia. The invention is also directed to the administration of a nitric oxide synthase substrate to a subject previously administered a nitric oxide synthase inhibitor, in order to selectively inhibit tumor perfusion. In a specific example, administration of cell free hemoglobin, a nitric oxide scavenger, in conjunction with mitomycin C, a hypoxic cytotoxin, results in a significant delay in tumor growth of a human tumor xenograft in a mouse compared to mitomycin C alone. In another example, the administration of an inhibitor of nitric oxide synthase followed by the administration of a substrate of the enzyme causes a specific irreversible reduction of tumor blood flow, while normal blood flow is restored.
Methods For Improving Therapeutic Effectiveness Of Agents For The Treatment Of Solid Tumors And Other Disorders
US Patent:
5612310, Mar 18, 1997
Filed:
May 24, 1993
Appl. No.:
8/066756
Inventors:
Mark W. Dewhirst - Chapel Hill NC
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beauford NC
Joseph DeAngelo - Hamtramck MI
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beauford NC
Joseph DeAngelo - Hamtramck MI
Assignee:
Duke University - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
International Classification:
A61K 3816
US Classification:
514 6
Abstract:
The present invention is directed to administration of a nitric oxide scavenger or a nitric oxide synthase inhibitor to enhance the effectiveness of tumor therapy with hypoxic or acidic chemotherapeutic agents or hyperthermia. In a specific example, administration of cell free hemoglobin, a nitric oxide scavenger, in conjunction with mitomycin C, a hypoxic cytotoxin, results in a significant delay in tumor growth of a human tumor xenograft in a mouse compared to mitomycin C alone.
Dr. Robert B Meyer, Cary NC - DDS (Doctor of Dental Surgery)
Specialties:
Orthodontics
Address:
1815 Kildaire Farm Rd SUITE C, Cary 27518
(919) 852-0009 (Phone)
(919) 852-0009 (Phone)
Languages:
English
Robert B Meyer, Cary NC
Specialties:
Dentist
Address:
1815 Kildaire Farm Rd, Cary, NC 27518
Methods For Improving Therapeutic Effectiveness Of Treatment Of Vascularization Disorders
US Patent:
6020308, Feb 1, 2000
Filed:
Jul 31, 1998
Appl. No.:
9/126930
Inventors:
Mark W. Dewhirst - Chapel Hill NC
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Robert E. Meyer - Cary NC
Joseph Bonaventura - Beaufort NC
Joseph DeAngelo - Hamtramck MI
Assignee:
Duke University - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
North Carolina State University - Raleigh NC
Apex Bioscience, Inc. - Durham NC
International Classification:
A61K 3816, A61K 3514
US Classification:
514 6
Abstract:
The present invention is directed to the use of an inhibitor of NO activity, such as a nitric oxide scavenger or an NO synthase inhibitor, as as an adjunct to treatment of inappropriate tissue vascularization disorders.