Inventors:
Matthieu F. Bal - Cadier en Keer, NL
Robert T. Ward - Madison WI, US
Scott L. Johnson - Madison WI, US
Michael Kaus - Madison WI, US
Assignee:
KONINKLIJKE PHILIPS ELECTRONICS N.V. - EINDHOVEN
International Classification:
G06Q 50/22
Abstract:
A system comprises a therapy tasks scheduling module () constructing a workflow schedule for performing a plurality of therapy tasks including dose optimizations, and a dose optimization module () performing a dose optimization in accordance with the workflow schedule to generate a therapy plan. The dose optimization module performs inverse radiation therapy planning that iteratively adjusts () a set of radiation therapy parameters () to optimize a simulated spatial dose distribution () respective to a set of radiation therapy objectives (). In some embodiments, at least some iterations update a region of a fluence map that is smaller than the entire fluence map. In some embodiments, at least some iterations optimize the simulated spatial dose distribution respective to a subset of the set of radiation therapy objectives. In some embodiments, the simulated spatial dose distribution has a nonuniform voxel size.