Inventors:
Jonathan Braun - Tarzana CA, US
Madhuri Wadehra - Fontana CA, US
Sathima Natarajan - Los Angeles CA, US
Robert Soslow - New York NY, US
International Classification:
A61K 33/24, C12Q 1/68, G01N 33/53, A61K 31/4355, A61K 31/56, A61K 31/7088, A61P 35/00
US Classification:
424649, 435 6, 435 71, 435 792, 514280, 514171, 514 44 R, 514364, 514383, 435 723, 514362, 514363
Abstract:
The present invention discloses methods of using endothelial membrane protein 2 (EMP2) as a biomarker for stratification of endometrial premalignancy, diagnosing, staging and imaging of endometrial neoplasia. Further, methods for identifying pharmaceutical/therapeutic modalities are described, including compositions which modulate glycolipid-enriched lipid raft microdomains (GEMs).