ROBERT A GALEMMO
Real Estate Commission in Paoli, PA
License number
Pennsylvania RS298233
Category
Real Estate Commission
Type
Real Estate Salesperson-Standard
Address
Address
Paoli, PA 19301
Professional information
Immobilized N-Substituted Tricyclic 3-Aminopyrazoles For The Identification Of Biomolecular Targets
US Patent:
2005013, Jun 16, 2005
Filed:
Nov 10, 2004
Appl. No.:
10/986500
Inventors:
Chih Ho - Lansdale PA, US
Robert Galemmo - Paoli PA, US
Dana Johnson - Upper Black Eddy PA, US
Jay Mei - North Wales PA, US
Stanley Belkowski - Norristown PA, US
Richard Connors - Harleysville PA, US
Robert Galemmo - Paoli PA, US
Dana Johnson - Upper Black Eddy PA, US
Jay Mei - North Wales PA, US
Stanley Belkowski - Norristown PA, US
Richard Connors - Harleysville PA, US
International Classification:
A61K031/7056, A61K031/427, A61K031/422, A61K031/4162, C07H017/00, C07D417/02, C07D413/02
US Classification:
514023000, 514365000, 514374000, 514406000, 536017400, 548181000, 548215000
Abstract:
The present invention relates to immobilized N-substituted tricyclic 3-aminopyrazole compounds of Formula 1 as tools for the identification of bimolecular targets in cells of therapeutic significance, profiling the selectivity of compounds, prediction of possible related toxicities and exploration of mechanisms of action in biological systems for therapeutic indications related to compounds. These agents can be used to identify biomolecules with the potential to interact with the immobilized reagent. The identified biomolecule may be then be used as a therapeutic target, serve as a marker of drug action, or alternatively describe an untoward or toxic potential of the immobilized agent.
N-Substituted Tricyclic 3-Aminopyrazoles As Anti-Mitotic Tubulin Polymerization Inhibitors
US Patent:
7816390, Oct 19, 2010
Filed:
Jan 29, 2008
Appl. No.:
12/021535
Inventors:
Robert A. Galemmo - Paoli PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Umar S. M. Maharoof - North Wales PA, US
Jay M. Mei - North Wales PA, US
Robert W. Tuman - Chalfont PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Umar S. M. Maharoof - North Wales PA, US
Jay M. Mei - North Wales PA, US
Robert W. Tuman - Chalfont PA, US
Assignee:
Janssen Pharmaceutica NV
International Classification:
A61K 31/416, C07D 231/54
US Classification:
514405, 5483591
Abstract:
The invention is directed to compounds having the following structures:.
Acylhydrazones As Kinase Modulators
US Patent:
7662824, Feb 16, 2010
Filed:
Mar 16, 2006
Appl. No.:
11/377077
Inventors:
Kristi Leonard - West Chester PA, US
Tianbao Lu - Churchville PA, US
Robert W. Tuman - Chalfont PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Richard W. Connors - Harleysville PA, US
Richard S. Alexander - Newark DE, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Thomas P. Markotan - Morgantown PA, US
Tianbao Lu - Churchville PA, US
Robert W. Tuman - Chalfont PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Richard W. Connors - Harleysville PA, US
Richard S. Alexander - Newark DE, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Thomas P. Markotan - Morgantown PA, US
Assignee:
Janssen Pharmaceutica NV - Beerse
International Classification:
A61K 31/496, A61K 31/404, C07D 405/14, C07D 405/12, C07D 407/14
US Classification:
51425409, 514414, 514418, 514422, 514323, 514469, 514416, 544373, 544144, 546201, 548454, 548483, 548518, 548525, 548490, 549462
Abstract:
The invention is directed to acylhydrazones compounds of Formula I:.
Triazolopyridazines As Kinase Modulators
US Patent:
8030305, Oct 4, 2011
Filed:
Dec 18, 2006
Appl. No.:
11/612020
Inventors:
Tianbao Lu - Churchville PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Assignee:
Janssen Pharmaceutica N.V.
International Classification:
C07D 487/04, A61K 31/5025, A61P 35/00
US Classification:
514248, 544236
Abstract:
The invention is directed to triazolopyridazine compounds of Formula I:.
Triazolopyridazine Compounds
US Patent:
8173654, May 8, 2012
Filed:
Aug 7, 2008
Appl. No.:
12/187524
Inventors:
Tianbao Lu - Churchville PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Richard Alexander - Newark DE, US
Richard W. Connors - Harleysville PA, US
Maxwell D. Cummings - Wayne PA, US
Robert A. Galemmo - Paoli PA, US
Heather Rae Hufnagel - Glenmoore PA, US
Dana L. Johnson - Upper Black Eddy PA, US
Ehab Khalil - West Chester PA, US
Kristi A. Leonard - Flourtown PA, US
Thomas P. Markotan - Morgantown PA, US
Anna C. Maroney - Media PA, US
Jan L. Sechler - Doylestown PA, US
Jeremy M. Travins - Downingtown PA, US
Robert W. Tuman - Chalfont PA, US
Assignee:
Janssen Pharmaceutica N.V. - Beerse
International Classification:
A61K 31/4985, C07D 487/04, A61P 3/10, A61P 17/06, A61P 25/18, A61P 19/02, A61P 9/10, A61P 9/00, A61P 35/00
US Classification:
514248, 544236
Abstract:
The invention is directed to triazolopyridazine compounds of Formula I:.