Inventors:
Robert E. Cohen - Jamaica Plain MA, US
Prem V. Pavoor - Somerville MA, US
Anuj Bellare - Brighton MA, US
Brian P. Gearing - Berkeley CA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61L 27/00, A61F 2/28
US Classification:
427 226, 427 21, 427 224, 427532, 427535, 623 1611, 623 1811
Abstract:
One aspect of the present invention relates to an implantable medical device comprising a surface coated with a polyelectrolyte multilayer, wherein said surface is glass, metal, plastic, polymer, or fiberglass. Another aspect of the present invention involves a method of preparing a PEM-coated implantable medical device, comprising the step of applying a film to a surface of an implantable medical device, wherein said film comprises a polyelectrolyte multilayer and said surface is glass, metal, plastic, polymer, or fiberglass. Another aspect of the present invention involves a method of reducing the wear between two contacting materials, comprising the step of moving a first material in contact with a second material in an environment, wherein a first surface of said first material is in contact with a second surface of said second material, wherein said first surface, said second surface, or both is coated with a polyelectrolyte multilayer, thereby decreasing the wear of said first material, said second material, or both compared to the wear in the absence of said polyelectrolyte multilayer.