Inventors:
J. Thomas Buckley - Victoria, CA
Robert A. Brodsky - Ruxton MD
Assignee:
University of Victoria Innovation and Development Corporation - Victoria
Johns Hopkins University - Baltimore MD
International Classification:
G01N 3353
US Classification:
435 724, 435 4, 435 77, 435 79, 435 4052, 435 691, 4352523, 43525411, 4353201, 435325, 530350, 536 231, 536 235, 436117, 436503, 436969
Abstract:
The present invention relates to toxins that specifically bind to GPI anchored proteins. More specifically, the present invention encompasses the uses of such toxins to detect the presence or absence of GPI anchored proteins. In one embodiment the present invention can be used to detect the presence of paroxysmal nocturnal hemoglobinuria.