Inventors:
Rishi Arora - Chicago IL, US
David E. Zembower - La Grange IL, US
International Classification:
A61K 31/551, A61K 31/135, A61K 31/404, A61K 31/22, A61K 31/5377, A61K 31/18, A61K 31/24, A61K 31/16, A61K 31/165, A61K 31/352, A61K 31/437, A61K 31/44, A61K 31/522, A61K 31/215, A61K 31/445, A61K 31/4725, A61K 31/4025, A61K 31/4545, A61P 9/06, A61K 31/47
US Classification:
514220, 514312, 514651, 514415, 514546, 514652, 5142362, 514605, 514538, 514629, 514620, 514456, 514603, 5142315, 514309, 514304, 514291, 514357, 51426334, 514529, 514534, 514530, 514317, 514307, 514422, 514316, 514318
Abstract:
The present invention provides compositions and methods for treating or preventing atrial fibrillation (AF). In particular, the present invention provides administration of muscarinic receptor antagonists (e.g., M2-selective muscarinic receptor blockers), administered alone or in combination with other therapeutic agents (e.g., beta-adrenergic receptor blockers) to treat and/or prevent atrial fibrillation.