Inventors:
Riley S. Rees - Ann Arbor MI, US
Cynthia Marcelo - Ann Arbor MI, US
Belinda Adamson - Ann Arbor MI, US
Lenore Rhodes - Ann Arbor MI, US
Beverly Marchant - Ann Arbor MI, US
William J. Lindblad - Farmington MI, US
Robert Gilmont - Ann Arbor MI, US
Warren Garner - Ann Arbor MI, US
Cynthia Zuccaro - Dexter MI, US
Thomas E. Taddonio - Manchester MI, US
Assignee:
Regents of the University of Michigan - Ann Arbor MI
Wayne State University - Detroit MI
International Classification:
A61F013/00, A01N025/34, A61K009/14, A61K009/20
US Classification:
424443, 424449, 424402, 424489, 424484, 424464
Abstract:
Devices and methods for enhancing the healing of wounds, especially chronic wounds (e. g. , diabetic wounds), involving the use of keratinocytes are described. Keratinocytes are grown on a transplantable solid support (e. g. , collagen-coated beads), and the keratinocyte-coated solid support is placed in an enclosure. The enclosure, in turn, is placed in the wound for use as an interactive wound healing promoter.