Inventors:
Alonzo H. Ross - Shrewsbury MA, US
Candace Gilbert - Worcester MA, US
Richard Moser - Worcester MA, US
Assignee:
University of Massachusetts - Shrewsbury MA
International Classification:
A61K 31/63, A61K 31/4188, A61K 31/175, A61K 31/553, A61P 35/00
US Classification:
514155, 51421109, 514393, 514589
Abstract:
Described are methods for treating cancers, e. g. , glioblastoma, including administering an inhibitor of Notch signalling, e. g. , a gamma secretase inhibitor, in combination with a chemotherapeutic agent.