Inventors:
David J. Yang - Sugar Land TX, US
Saady Kohanim - Sugar Land TX, US
Dong-Fang Yu - Houston TX, US
Richard Mendez - Houston TX, US
E. Edmund Kim - Houston TX, US
Assignee:
The Board of Regents of the University of Texas System - Austin TX
International Classification:
A61K 51/04, A61K 49/00
US Classification:
424 165, 424 936, 424 942, 424 95, 424 945
Abstract:
Compositions and methods for imaging and for chemotherapy and radiotherapy are disclosed. More particularly, the invention concerns agents comprising a targeting moeity comprising a beta-adrenergic receptor targeting compound conjugated or embedded with ethylenediamine. The present invention also concerns methods of application of such agents for imaging and treatment of cardiovascular diseases, and kits for preparing a radiolabeled therapeutic or diagnostic agent.