Inventors:
Richard Shadduck - Pittsburgh PA, US
International Classification:
A61K 35/14, A61K 39/00, A61K 31/573, A61K 31/5377, A61K 31/4745
US Classification:
424093700, 424277100, 514171000, 514232500, 514291000
Abstract:
Methods and formulations for the treatment of malignancies. Assessment of the incidence and scope of MC in control and cancer populations provides for the development of cellular therapy approaches to hematologic malignancies that are expected to be well tolerated immunologically. Studies will confirm that parous females who display MC are able to tolerate donor cells from their male offspring immunologically. Studies will explore the use of MC offspring donor cells in cellular therapy for the treatment of hematologic and other malignancies.