Inventors:
Carol Watkins - Cambridge MA, US
Richard J. Wurtman - Boston MA, US
Assignee:
Massachusetts Institute of Technology - Cambridge MA
International Classification:
A61K 31/70, A61K 38/18, C07K 14/48
Abstract:
The present invention provides methods of stimulating or enhancing production of a cellular membrane, improving a cognitive function or a neurological function, treating or ameliorating a decline in a cognitive function or a neurological function, increasing cytidine levels, or treating a neurological disorder in a subject, comprising administering a uridine, a uridine precursor, or a derivative or metabolite thereof to the subject. The invention also provides methods of improving neural function, comprising contacting the neuron with a uridine, a uridine precursor, or a derivative or metabolite thereof.