RICHARD JAMES HARWOOD
Pharmacy at Franklin Mills Blvd, Philadelphia, PA

4730013, Mar 8, 1988

Mar 2, 1987

7/020616

Joseph V. Bondi - Collegeville PA
Richard J. Harwood - Bensalem PA

Merck & Co., Inc. - Rahway NJ

A61K 922, C08L 126

524 42

Ocular inserts with or without pharmacologically active agents comprising low molecular weight polymers have a lower propensity to cause blurred vision compared with inserts prepared from high molecular weight hydroxypropyl cellulose. When an enteric coating material is included as a constituent of the matrix there is provided a means for controlling and predicting dissolution rates of the insert to yield a prolonged residence time.

4179497, Dec 18, 1979

Nov 13, 1978

5/959550

Edward M. Cohen - Beaumont, FR
Wayne M. Grim - Doylestown PA
Richard J. Harwood - Philadelphia PA
Gunvant N. Mehta - Lansdale PA

Merck & Co., Inc. - Rahway NJ

A61K 922, A61K 926

424 22

Solid unit dosage medicaments which are suitable for use in animals and humans are prepared with hydroxypropyl cellulose as the primary formulating excipient. These medicaments are particularly suitable for ophthalmic use since they are slowly but completely water soluble when they are inserted in the cul-de-sac of the eye and thus provide for a convenient means of prolonged treatment of the eye with concomitant reduced dosing frequency.

4975281, Dec 4, 1990

Jan 30, 1989

7/303871

Richard J. Harwood - Bensalem PA
Edward V. Henry - Peapack NJ
Joseph S. Sonk - Cherry Hill NJ
Luke T. H. Foo - Skillman NJ
Jay L. Rheingold - Marlboro NJ
Robert C. deGroof - Doylestown PA

E. R. Squibb & Sons, Inc. - Princeton NJ

A61K 928

424441

In accordance with the present invention a novel oral composition and method of using same for the treatment of ulcers and other gastrointestinal disorders is disclosed. The composition comprises an agent capable of forming an ulcer-adherent protective complex in an acid environment combined with one or more alkaline materials in a total amount sufficient to substantially prevent the formation of such a complex in the mouth and adherence of such a complex to the buccal mucosa.

5026709, Jun 25, 1991

Jun 7, 1988

7/203435

Richard J. Harwood - Bensalem PA
Gunvant N. Mehta - Lansdale PA
Ramesh C. Jhawar - Yardley PA
Liang-Lii Huang - Maple Glen PA
Wayne M. Grim - Doylestown PA
Shun P. Li - Upper Darby PA

Rorer Pharmaceutical Corporation - Fort Washington PA

A01N 4390, A01K 3152

514263

A method for the preparation of a sustained release pharmaceutical composition comprising forming a fluidized ring of said particles and contacting said particles maintained suspended in said ring with a liquid composition containing a pharmaceutically active material and an alkali-soluble material.

4439194, Mar 27, 1984

Sep 8, 1981

6/300370

Richard J. Harwood - Bensalem PA
Joseph V. Bondi - Collegeville PA

Merck & Co., Inc. - Rahway NJ

A61L 1506

604890

A drug delivery system designed to deliver water and drug to the site of administration is composed of a core of an aqueous solubulizing system in a wax housing, which melts at body temperature, surrounded by a matrix of drug and water-dispersible excipients. The entire unit may also be coated with a semi-permeable membrane to modulate drug release.

4744986, May 17, 1988

Mar 7, 1986

6/837527

Joseph R. Luber - Lafayette Hills PA
Kenneth M. Feld - Chalfont PA
Richard J. Harwood - Bensalem PA
Wayne M. Grim - Doylestown PA

Rorer Pharmaceutical Corporation - Fort Washington PA

A61K 3110, A61K 3312, A61K 3308

424156

A process for the preparation of a viscosity-stable antacid composition containing an alginic acid salt comprising reacting an antacid material with said salt at elevated temperatures to form a reaction product and recovering said reaction product in stabilized form.

5112813, May 12, 1992

Mar 7, 1988

7/164551

Joseph R. Luber - Lafayette Hills PA
Kenneth M. Feld - Chalfont PA
Richard J. Harwood - Bensalem PA
Wayne M. Grim - Doylestown PA

Rhone-Poulenc Rorer Pharmaceuticals Inc. - Fort Washington PA

A61K 31715, A61K 3110, A61K 3308

514 54

A process for the preparation of a viscosity-stable antacid composition containing an alginic acid salt comprising reacting an antacid material with said salt at elevated temperatures to form a reaction product and recovering said reaction product in stabilized form.

4223788, Sep 23, 1980

Nov 16, 1978

5/961429

Arthur Jaeger - West Chester PA
Richard Gunderlock - Lederach PA
Richard J. Harwood - Philadelphia PA

Merck & Co., Inc. - Rahway NJ

B65D 3700, B65D 5500

206468

A rigid blister package includes a rigid thermoformed plastic cover piece and a flexible backing sheet, a score line for opening said package, and a slide fastener for reclosing the blister package, along with stops to hold the slide fastener in the open or closed position.

4230105, Oct 28, 1980

Nov 13, 1978

5/960354

Richard J. Harwood - Philadelphia PA

Merck & Co., Inc. - Rahway NJ

A61L 1500

128156

An improved method for the topical administration of systemically or locally active drugs utilizes a bandage containing one or more layers including a drug useful in the treatment of disease and a heat-generating substance, each dispersed intimately throughout said bandage layers.

4283393, Aug 11, 1981

Mar 13, 1979

6/020125

Arthur K. Field - North Wales PA
Richard J. Harwood - Philadelphia PA

Merck & Co., Inc. - Rahway NJ

A61K 3170

424180

Virus infections of eye, skin and mucous membrane tissue are effectively treated by controlled release topical application of interferon inducers.