Inventors:
Ryuzo Ueda - Aichi, JP
Takashi Ishida - Aichi, JP
Shiro Akinaga - Tokyo, JP
Toshihiko Ishii - Shizuoka, JP
Daniel Jones - Houston TX, US
Richard Ford - Houston TX, US
Jahan Khalili - Houston TX, US
Kaushali Patel - Houston TX, US
Assignee:
Kyowa Hakko Kogyo Co., Ltd. - Chiyoda-ku
Board of Regents, The University of Texas System - Austin TX
International Classification:
A61K 39/395
Abstract:
The present invention relates to a method for injuring or depleting a B-cell neoplasm cell or a Hodgkin's lymphoma cell and a method for treating B-cell neoplasm or Hodgkin's lymphoma, wherein each method comprises administering to a patient a monoclonal antibody which specifically binds to a human CC chemokine receptor 4 (CCR4) or an antibody fragment thereof.