RICHARD IVAN SENDEROFF
Pharmacy in Edmonds, WA
License number
Pennsylvania RP034260L
Category
Pharmacy
Type
Pharmacist
Address
Address
2
Edmonds, WA 98026
Pennsylvania
Pennsylvania
Personal information
See more information about RICHARD IVAN SENDEROFF at radaris.comName
Address
Phone
18823 81St Ave W, Edmonds, WA 98026
Mountlake Terrace, WA
18823 81St Ave W, Edmonds, WA 98026
19923 81St Pl W, Edmonds, WA 98026
Professional information
Thrombin Compositions
US Patent:
7393674, Jul 1, 2008
Filed:
Jun 21, 2005
Appl. No.:
11/157707
Inventors:
Shan Jiang - Sammamish WA, US
Richard I. Senderoff - Edmonds WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Richard I. Senderoff - Edmonds WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Assignee:
Zymogenetics, Inc. - Seattle WA
International Classification:
C12N 9/74
US Classification:
435214, 435 71, 530300, 530350
Abstract:
Compositions comprising thrombin and methods of preparing them are disclosed. The composition may be in the form of an aqueous solution at pH 5. 7-7. 4 consisting essentially of 0. 1 mg/mL to 5. 0 mg/mL thrombin, 2% to 4% (w/v) sucrose, 3. 5% to 5% (w/v) mannitol, 50 mM to 300 mM NaCl, 0-5 mM CaCl, 0. 03% to 1% (w/v) of a surfactant or high-molecular-weight polyethylene glycol, and a physiologically acceptable buffer, or may be in lyophilized form.
Thrombin Compositions
US Patent:
7473543, Jan 6, 2009
Filed:
Oct 6, 2006
Appl. No.:
11/539276
Inventors:
Shan Jiang - Sammamish WA, US
Richard I. Senderoff - Edmonds WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Richard I. Senderoff - Edmonds WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
C12N 9/74
US Classification:
435214, 435 71, 530300, 530350
Abstract:
Compositions comprising thrombin and methods of preparing them are disclosed. The composition may be in the form of an aqueous solution at pH 5. 7-7. 4 consisting essentially of 0. 1 mg/mL to 5. 0 mg/mL thrombin, 2% to 4% (w/v) sucrose, 3. 5% to 5% (w/v) mannitol, 50 mM to 300 mM NaCl, 0-5 mM CaCl, 0. 03% to 1% (w/v) of a surfactant or high-molecular-weight polyethylene glycol, and a physiologically acceptable buffer, or may be in lyophilized form.
Stabilized Thrombin Compositions
US Patent:
8071090, Dec 6, 2011
Filed:
Jun 13, 2008
Appl. No.:
12/138922
Inventors:
Richard I. Senderoff - Edmonds WA, US
Shan Jiang - Sammamish WA, US
Shan Jiang - Sammamish WA, US
Assignee:
Zymogenetics, Inc. - Princeton NJ
International Classification:
A61K 38/43
US Classification:
424 9464
Abstract:
Stabilized thrombin compositions, processes for preparing them, and kits comprising them are disclosed. The compositions comprise thrombin, a bacteriostatically effective amount of benzyl alcohol or chlorobutanol, and 0. 10%-5. 0% (w/v) sucrose in aqueous solution. The compositions are stable when stored at 2° C. -8° C. for four weeks or more.
Hemostatic Microspheres
US Patent:
2011012, May 26, 2011
Filed:
Mar 26, 2009
Appl. No.:
12/935114
Inventors:
Richard I. Senderoff - Edmonds WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Emily N. Rollins - Seattle WA, US
Steven D. Hughes - Kenmore WA, US
Richard M. Garcoa - Kirkland WA, US
Paul D. Bishop - Fall City WA, US
Gerald W. Lasser - Lynnwood WA, US
Jeffrey D. Meyer - Lake Forest Park WA, US
Emily N. Rollins - Seattle WA, US
Steven D. Hughes - Kenmore WA, US
Richard M. Garcoa - Kirkland WA, US
Paul D. Bishop - Fall City WA, US
Gerald W. Lasser - Lynnwood WA, US
Assignee:
ZYMOGENETICS, INC. - Seattle WA
International Classification:
A61K 9/14, C07K 14/00, A61K 47/42, A61K 38/48, A61K 35/16, A61P 7/00, B32B 5/16, A61M 5/31
US Classification:
604 82, 530354, 514774, 424530, 424 9464, 424499, 428402, 604187
Abstract:
Provided herein are hemostatic compositions. In one embodiment, the hemostatic composition includes cross-linked polymer microspheres, such as cross-linked gelatin microspheres with pores. In another embodiment, the hemostatic composition comprises an additive such as a wetting agent, a suspending agent, or both. The hemostatic compositions may also include a hemostatic agent such as thrombin, and may include a high concentration of thrombin. The hemostatic compositions may also include plasma. Also provided herein are devices for dispersing said hemostatic compositions in a diluent, and delivering said dispersed hemostatic composition. The hemostatic compositions may also fabricated with a selected geometry as administration suggests.