Inventors:
Douglas G. Batt - Wilmington DE
Richard S. Greenberg - Wayne NJ
Richard R. Harris - Wilmington DE
Assignee:
E. I. Du Pont de Nemours and Company - Wilmington DE
International Classification:
A61K 0000
Abstract:
Antiinflammatory carbinoloimidazoles are provided which have the formula: ##STR1## or a pharmaceutically acceptable salt thereof, wherein
R. sup. 1 and R. sup. 2 independently are H, F, Cl, Br, CH. sub. 3, CF. sub. 3 or S(O). sub. n R. sup. 3 where n is 0, 1 or 2 and
R. sup. 3 is alkyl of 1-4 carbon atoms;
R. sup. 4 is H or alkyl of 1-4 carbon atoms with the proviso that R. sup. 4 is H when m is 2 or 3; and
m is 1 to 3.
The carbinoloimidazoles are preferably administered as topical antiinflammatory compositions.