RICHARD H DEAN
Plumbers in Manchester, NH
License number
Massachusetts 27548
Issued Date
Dec 13, 2002
Expiration Date
May 1, 2004
Type
Apprentice Plumber
Address
Address
Manchester, NH 03103
Personal information
See more information about RICHARD H DEAN at radaris.comName
Address
Phone
4 Riviera Rd, Hudson, NH 03051
64 Gosselin Rd, Manchester, NH 03103
58 Sand Hill Rd, Gilford, NH 03249
Professional information
Radioactively Labeled Somatostatin-Derived Peptides For Imaging And Therapeutic Uses
US Patent:
5814298, Sep 29, 1998
Filed:
Jun 6, 1995
Appl. No.:
8/465764
Inventors:
Richard T. Dean - Bedford NH
John Lister-James - Bedford NH
John Lister-James - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614
US Classification:
424 169
Abstract:
This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic agents. Specifically, the invention relates to peptide derivatives and analogs of somatostatin, and embodiments of such peptides labeled with technetium-99m (Tc-99m), as well as methods and kits for making, radiolabeling and using such peptides to image sites in a mammalian body. The invention also relates to peptide derivatives and analogues of somatostatin labeled with rhemium-186 (. sup. 186 Re) and rhenium-188 (. sup. 188 Re), and methods and kits for making, radiolabeling and using such peptides therapeutically in a mammalian body.
Technetium-99M Labeled Peptides For Imaging
US Patent:
5443815, Aug 22, 1995
Filed:
Nov 27, 1991
Appl. No.:
7/807062
Inventors:
Richard T. Dean - Bedford NH
William McBride - Manchester NH
Scott Buttram - Derry NH
William McBride - Manchester NH
Scott Buttram - Derry NH
Assignee:
Diatech, Inc. - Londonderry NH
International Classification:
A61K 5108
US Classification:
424 141
Abstract:
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention provides peptides which bind Tc-99m and which can be targeted to specific sites within a mammalian body.
Technetium-99M Labeled Peptides For Imaging Inflammation
US Patent:
6017510, Jan 25, 2000
Filed:
Jun 27, 1994
Appl. No.:
8/266178
Inventors:
Richard T. Dean - Bedford NH
Robert S. Lees - Brookline MA
Scott Buttram - Derry NH
Robert S. Lees - Brookline MA
Scott Buttram - Derry NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614, G01N 3353, G01N 33567
US Classification:
424 169
Abstract:
This invention relates to radiolabeled peptides and methods for producing such peptides. Specifically, the invention relates to technetium-99m (Tc-99m) labeled leukocyte-binding peptides, methods and kits for making such peptides, and methods for using such peptides to image sites of infection and inflammation in a mammalian body.
Somatostatin Analogs
US Patent:
6183722, Feb 6, 2001
Filed:
Oct 19, 1999
Appl. No.:
9/420866
Inventors:
Richard T. Dean - Bedford NH
John Lister-James - Bedford NH
John Lister-James - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614
US Classification:
424 169
Abstract:
This invention relates to therapeutic reagents and peptides, including radiotherapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing labeled radiodiagnostic agents. Specifically, the invention relates to cyclic peptide derivatives and analogs of somatostatin, and embodiments of such peptides radiolabeled with a radioisotope, as well as methods and kits for making, radiolabeling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention also specifically relates to cyclic peptide derivatives and analogues of somatostatin radiolabeled with cytotoxic radioisotopes such as rhenium-186 (. sup. 186 Re) and rhenium-188 (. sup. 188 Re) for use as radiotherapeutic agents.
Radioactive Peptides
US Patent:
5620675, Apr 15, 1997
Filed:
Jul 21, 1993
Appl. No.:
8/095760
Inventors:
William McBride - Manchester NH
Richard T. Dean - Bedford NH
Richard T. Dean - Bedford NH
Assignee:
Diatech, Inc. - Londonderry IL
International Classification:
A61K 3831, A61K 3800, A61K 5100
US Classification:
424 169
Abstract:
This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for producing label radiodiagnostic agents. Specifically, the invention relates to linear peptide derivatives and analogs of somatostatin, and embodiments of such peptides radiolabeled with a radioisotope, as well as methods and kits for making, radiolabeling and using such peptides for radiodiagnostic and radiotherapeutic purposes. The invention specifically relates to linear peptide derivatives and analogues of somatostatin radiolabeled with technetium-99m and uses thereof as scintigraphic imaging agents. The invention so specifically relates to liner peptide derivatives and analogues of somatostatin radiolabeled with cytotoxic radioisotopes such as rhenium-186 (. sup. 186 Re) and rhenium-188 (. sup. 188 Re) for use as radiotherapeutic agents.
Technetium-99M Labeled Peptides For Imaging
US Patent:
5922303, Jul 13, 1999
Filed:
Jun 6, 1995
Appl. No.:
8/468964
Inventors:
Richard T. Dean - Bedford NH
Scott Buttram - Derry NH
William McBride - Manchester NH
John Lister-James - Bedford NH
Edgar R. Civitello - Londonderry NH
Scott Buttram - Derry NH
William McBride - Manchester NH
John Lister-James - Bedford NH
Edgar R. Civitello - Londonderry NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614
US Classification:
424 169
Abstract:
This invention relates to radiolabeled peptides and methods for producing such peptides. Specifically, the invention relates to peptides, methods and kits for making such peptides, and methods for using such peptides to image sites in a mammalian body labeled with technetium-99m (Tc-99m) via a radiolabel-binding moiety which forms a neutral complex with Tc-99m.
Pharmaceutical Compositions For Imaging And Treating Thrombi
US Patent:
6028056, Feb 22, 2000
Filed:
Feb 6, 1998
Appl. No.:
9/020086
Inventors:
Richard T. Dean - Bedford NH
John Lister-James - Bedford NH
John Lister-James - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 3800, A61K 3816
US Classification:
514 12
Abstract:
The invention provides novel precursor reagents used in production of imaging agents derived from apcitide. Imaging agents made using the precursor reagents of the invention are useful for in vivo detection and diagnosis of thrombi. The precursor reagents of the invention may also be used in production of antithrombotic agents derived from apcitide.
Calcitonin Receptor Binding Reagents
US Patent:
6086850, Jul 11, 2000
Filed:
May 1, 1998
Appl. No.:
9/071090
Inventors:
Richard T. Dean - Bedford NH
Larry R. Bush - Exeter NH
Daniel A. Pearson - Bedford NH
John Lister-James - Bedford NH
Larry R. Bush - Exeter NH
Daniel A. Pearson - Bedford NH
John Lister-James - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614
US Classification:
424 169
Abstract:
This invention relates to calcitonin receptor binding reagents comprising compounds which are covalently linked to a radiometal chelator. The invention is embodied as calcitonin receptor binding peptide derivatives and analogues of calcitonin which may be radiolabeled with a suitable isotope and used as radiodiagnostic or radiotherapeutic agents. Methods and kits for making, radiolabeling and using such reagents diagnostically and therapeutically in a mammalian body are also provided.
Radiolabeled Glucans Which Bind To Leukocytes, Sites Of Infection, Inflammation, Atherosclerosis, Or Cancer
US Patent:
5879660, Mar 9, 1999
Filed:
Dec 27, 1995
Appl. No.:
8/579449
Inventors:
Richard T. Dean - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 5100, A61M 3614
US Classification:
424 173
Abstract:
This invention relates to radiodiagnostic agents and reagents for preparing such agents, and also methods for producing radiolabeled radiodiagnostic agents. Specifically, the invention relates to technetium-99m (. sup. 99m Tc) labeled agents, methods and kits for making the agents, and methods for using the agents to image pathological sites, including sites of infection, inflammation, cancer and atherosclerosis in a mammalian body. Specifically the agents and reagents are derivatives of oligosaccharides, more specifically. beta. -glucans.
Technetium-99M Labeled Polypeptides For Imaging
US Patent:
5654272, Aug 5, 1997
Filed:
Jun 22, 1994
Appl. No.:
8/263758
Inventors:
Richard T. Dean - Bedford NH
Assignee:
Diatide, Inc. - Londonderry NH
International Classification:
A61K 3800, C07K 500, C07K 700
US Classification:
514 12
Abstract:
The invention relates to radiolabeled imaging of a mammalian body. The invention in particular provides for reagents labeled with technetium-99m for such imaging. The invention provides peptides which bind technetium-99m and which can be targeted to specific sites within a mammalian body.