Inventors:
Richard Essner - Santa Monica CA, US
International Classification:
A61K 31/713, C40B 30/04, C12Q 1/68, A61K 31/7105, A61P 35/00
US Classification:
424 59, 514 44 A, 514 44 R, 435 614, 506 9, 435 613
Abstract:
The invention discloses a method of identifying a gene associated with stage III primary cancer or lymph node metastasis. The genes so identified include CAV1, CST3, LIMK1, MMP2, MMP15, VEGF, ETV4, MMP9, PIK3C2B, and SERPIN1. Also disclosed are methods for diagnosis, prognosis, and treatment of cancer. The invention further discloses compositions for preventing and treating diseases.