DR. RICHARD E. GREGG, M.D.
Osteopathic Medicine at Linden Ln, Pennington, NJ
License number
New Jersey D0030331
Category
Osteopathic Medicine
Type
Endocrinology, Diabetes & Metabolism
Address
Address
7 Linden Ln, Pennington, NJ 08534
Phone
(609) 737-3066
Professional information
Microsomal Triglyceride Transfer Protein
US Patent:
6492365, Dec 10, 2002
Filed:
Jun 7, 1995
Appl. No.:
08/486929
Inventors:
Daru Young Sharp - Perrineville NJ
Richard E. Gregg - Pennington NJ
Richard E. Gregg - Pennington NJ
Assignee:
Bristol-Myers Squibb Company - New York NY
International Classification:
C07D26106
US Classification:
514247, 514277
Abstract:
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Nucleic Acids Encoding Microsomal Trigyceride Transfer Protein
US Patent:
5595872, Jan 21, 1997
Filed:
Sep 3, 1993
Appl. No.:
8/117362
Inventors:
John R. Wetterau - Langhorne PA
Daru Y. Sharp - Perrineville NJ
Richard E. Gregg - Pennington NJ
Scott A. Biller - Ewing NJ
John K. Dickson - Mount Holly NJ
R. Michael Lawrence - Yardley PA
John E. Lawson - Wallingford CT
Henry M. Holava - Meriden CT
Richard A. Partyka - Neshanic NJ
Daru Y. Sharp - Perrineville NJ
Richard E. Gregg - Pennington NJ
Scott A. Biller - Ewing NJ
John K. Dickson - Mount Holly NJ
R. Michael Lawrence - Yardley PA
John E. Lawson - Wallingford CT
Henry M. Holava - Meriden CT
Richard A. Partyka - Neshanic NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
C12Q 170, C07H 2102, C12N 1579, C12N 510
US Classification:
435 6
Abstract:
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Method Of Inhibiting Or Treating Phytosterolemia With An Mtp Inhibitor
US Patent:
6057339, May 2, 2000
Filed:
Jan 10, 1998
Appl. No.:
9/005430
Inventors:
Richard E. Gregg - Pennington NJ
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31445, A61K 3121
US Classification:
514325
Abstract:
A method is provided for inhibiting onset of or treating phytosterolemia by administering to a patient an MTP inhibitor, alone or optionally, in combination with another cholesterol lowering drug, such as pravastatin.
Method Of Treating Acid Lipase Deficiency Diseases With An Mtp Inhibitor And Cholesterol Lowering Drugs
US Patent:
6066653, May 23, 2000
Filed:
Jan 10, 1998
Appl. No.:
9/005437
Inventors:
Richard E. Gregg - Pennington NJ
John R. Wetterau - Langhorne PA
John R. Wetterau - Langhorne PA
Assignee:
Bristol-Myers Squibb Co. - Princeton NJ
International Classification:
A61K 31445, A61K 3121
US Classification:
514325
Abstract:
A method is provided for inhibiting or treating diseases associated with acid lipase deficiency by administering to a patient an MTP inhibitor, alone or optionally, in combination with another cholesterol lowering drug, such as pravastatin.
Method For Lowering Serum Lipid Levels Employing An Mtp Inhibitor In Combination With Another Cholesterol Lowering Drug
US Patent:
5883109, Mar 16, 1999
Filed:
May 12, 1997
Appl. No.:
8/854311
Inventors:
Richard E. Gregg - Pennington NJ
Hubert G. Pouleur - Lawrenceville NJ
John R. Wetterau - Langhorne PA
Hubert G. Pouleur - Lawrenceville NJ
John R. Wetterau - Langhorne PA
Assignee:
Bristol-Myers Squibb Company - Princeton NJ
International Classification:
A61K 31445
US Classification:
514321
Abstract:
A method is provided for lowering serum lipids, cholesterol and/or triglycerides and thereby inhibiting atherosclerosis by administering to a patient an MTP inhibitor, in combination with a cholesterol lowering drug, such as pravastatin.
Microsomal Triglyceride Transfer Protein
US Patent:
5789197, Aug 4, 1998
Filed:
Jun 7, 1995
Appl. No.:
8/486924
Inventors:
John R. Wetterau - Langhorne PA
Daru Young Sharp - Perrineville NJ
Richard E. Gregg - Pennington NJ
Daru Young Sharp - Perrineville NJ
Richard E. Gregg - Pennington NJ
Assignee:
E. R. Squibb & Sons, Inc. - Princeton NJ
International Classification:
C12P 2102, C07K 1400, C12Q 100, C12Q 125
US Classification:
435 691
Abstract:
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.
Microsomal Triglyceride Transfer Protein
US Patent:
2003016, Sep 4, 2003
Filed:
Aug 21, 2001
Appl. No.:
09/933593
Inventors:
John Wetterau - Langhorne PA, US
Daru Sharp - Perrineville NJ, US
Richard Gregg - Pennington NJ, US
Scott Biller - Ewing NJ, US
John Dickson - Mount Holly NJ, US
R. Lawrence - Yardley PA, US
John Lawson - Wallingford CT, US
Henry Holava - Meriden CT, US
Richard Partyka - Neshanic NJ, US
Daru Sharp - Perrineville NJ, US
Richard Gregg - Pennington NJ, US
Scott Biller - Ewing NJ, US
John Dickson - Mount Holly NJ, US
R. Lawrence - Yardley PA, US
John Lawson - Wallingford CT, US
Henry Holava - Meriden CT, US
Richard Partyka - Neshanic NJ, US
International Classification:
A61K048/00, C07H021/04
US Classification:
514/044000, 536/023200
Abstract:
Nucleic acid sequences, particularly DNA sequences, coding for all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, expression vectors containing the DNA sequences, host cells containing the expression vectors, and methods utilizing these materials. The invention also concerns polypeptide molecules comprising all or part of the high molecular weight subunit of microsomal triglyceride transfer protein, and methods for producing these polypeptide molecules. The invention additionally concerns novel methods for preventing, stabilizing or causing regression of atherosclerosis and therapeutic agents having such activity. The invention concerns further novel methods for lowering serum liquid levels and therapeutic agents having such activity.