Inventors:
J. Torday - Rodondo Beach CA, US
Virender Rehan - Torrance CA, US
Richard Mink - Torrance CA, US
International Classification:
A61K 31/557, A61K 31/4439, A61K 31/426
US Classification:
514340000, 514369000, 514573000
Abstract:
This invention pertains to the discovery that Parathyroid Hormone-related Protein (PTHrP) can be detect and/or stage, and/or treat chronic lung diseases. In particular, it was discovered that PTHrP levels in broncho-alveolar lavage are indicative of lung “health” and “disease, and can be used to predict lung disease in patients at risk of chronic lung disease and/or to evaluate the efficacy of a ventilation regime.