Inventors:
Beverly L. Davidson - Iowa City IA
Richard Anderson - Coralville IA
Ronald Haskell - West Liberty IA
Haibin Xia - Iowa City IA
Assignee:
University of Iowa Research Foundation - Iowa City IA
International Classification:
C12N 1564
US Classification:
4352351, 435 9142, 4353201, 435325, 435462, 435463, 435466, 435475, 435476, 435477, 536 2372
Abstract:
The invention provides a novel Adenovirus backbone plasmid, which when co-transfected with a shuttle vector, allows for production of recombinant viruses quickly and easily. The present invention also provides host cells and a cloning system for generating recombinant adenoviruses.