RHEA M SUMPTER, M.D.
Osteopathic Medicine at Harry Hines Blvd, Dallas, TX
License number
Texas P4516
Category
Osteopathic Medicine
Type
Infectious Disease
License number
Texas P4516
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
5323 Harry Hines Blvd, Dallas, TX 75390
Phone
(214) 645-2800
(214) 645-2808 (Fax)
(214) 645-2808 (Fax)
Personal information
See more information about RHEA M SUMPTER at radaris.comName
Address
Phone
10710 Saint Lazare Dr, Dallas, TX 75229
9946 Mixon Dr, Dallas, TX 75220
Organization information
See more information about RHEA M SUMPTER at bizstanding.comRhea M Sumpter MD
5323 Harry Hines Blvd, Dallas, TX 75390
Categories:
Infectious Disease Physicians & Surgeons, Internal Medicine Physicians & Surgeons
Phone:
(214) 648-5460 (Phone)
Professional information
Prenylation Inhibitors Reduce Host Cell Permissiveness To Viral Replication
US Patent:
2005008, Apr 21, 2005
Filed:
Oct 21, 2003
Appl. No.:
10/690891
Inventors:
Michael Brown - Dallas TX, US
Jin Ye - Dallas TX, US
Chunfu Wang - Dallas TX, US
Rhea Sumpter - Dallas TX, US
Joseph Goldstein - Dallas TX, US
Michael Gale - Dallas TX, US
Jin Ye - Dallas TX, US
Chunfu Wang - Dallas TX, US
Rhea Sumpter - Dallas TX, US
Joseph Goldstein - Dallas TX, US
Michael Gale - Dallas TX, US
International Classification:
A61K031/401, A61K031/366, A61K031/225
US Classification:
514423000, 514460000, 514548000
Abstract:
Permissiveness of human cells to replication of susceptible pathogenic human viruses is reduced by treating the cells with a selective inhibitor of prenylation of a host cell protein. Target viruses, especially Flaviviridae, are predetermined to lack a CXXX box and prenylated viral protein, and to be replication-dependent on host protein prenylation. The general method comprises (a) contacting human cells subject to infection by the virus with an effective amount of a selective inhibitor of a prenylation enzyme of the cells; and (b) confirming a resultant reduction in permissiveness of the cells to replication of the virus. Targeted enzymes include prenyl biosynthetic enzyme like HMG CoA reductase farnesyl and/or geranylgeranyl transferase enzymes.
Dr. Rhea M Sumpter, Dallas TX - MD (Doctor of Medicine)
Specialties:
Infectious Disease Medicine
Age:
49
Address:
Dallas
5323 Harry Hines Blvd, Dallas 75390
(214) 648-3111 (Phone), (214) 648-9050 (Fax)
5323 Harry Hines Blvd, Dallas 75390
(214) 648-3111 (Phone), (214) 648-9050 (Fax)
Certifications:
Infectious Disease, 2012, Internal Medicine, 2010
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
University of Texas Southwestern Medical Center At Dallas
Graduated: 2002
University of Texas Southwestern Medical Center At Dallas
Graduated: 2002
Rhea Myers Sumpter, Dallas TX
Specialties:
Internal Medicine
Work:
House Staff & Gme
5201 Harry Hines Blvd, Dallas, TX 75235
5201 Harry Hines Blvd, Dallas, TX 75235
Education:
(2006)