Inventors:
Margo P. Cohen - New York NY
Rex S. Clements - Pineville PA
Assignee:
Exocell, Inc. - Philadelphia PA
International Classification:
A61K 3124
Abstract:
The present invention is directed to the prevention in vivo of post-secretory Amadori modifications in the Apo B molecule, as well as methods of using compounds that protect against these modifications in vivo to treat hypercholesterolemia and vascular dysfunction.