Inventors:
Rebecca A. Cox - San Antonio TX, US
D. Mitchell Magee - Dallas TX, US
F. Douglas Ivey - Watertown MA, US
Melanie D. Woitaske - La Vernia TX, US
Assignee:
The University of Texas System Board of Regents - Austin TX
International Classification:
C07K 1/00, C07K 16/00, C12P 21/08, C07H 21/04, A61K 39/00, A61K 38/00
US Classification:
530350, 5303886, 530300, 536 232, 536 242, 4241841
Abstract:
Disclosed are protein and peptide antigen and DNA compositions effective in generating immune responses against the pathogenic fungi spp. , the causative agents of coccidioidomycosis and Valley Fever. The invention thus provides protein and peptide antigens, DNA constructs, combinations and related biological compositions, and prophylactic and therapeutic methods of using such components and combinations to generate effective and protective immune responses against spp. , including.