DR. RAY WARREN EXLEY, M.D.
Anesthesiologist Assistant at Highridge Pl, Beverly Hills, CA

2011010, May 5, 2011

Nov 20, 2008

12/743535

Ray W. Exley - Beverly Hills CA, US

A61K 31/52, C07D 473/18, C07D 473/34, C07F 9/6561, A61K 31/522, A61P 37/02, A61P 25/00, A61P 31/22, A61P 21/02, A61P 21/00, A61P 29/00, A61P 13/12, A61K 31/675

514 81, 544276, 544277, 544244, 51426338

Anti-herpetic material such as 2-amino purine derivatives to prevent or treat autoimmune disease or a disease originating from an abnormal functioning of the sympathetic chain in a human subject. The disease is often of a tissue or organ associated with decreased blood flow to the tissue or organ (correlated with hypertonicity of the vessels feeding the tissue or organ). The treatment reduces inflammation, scarring, destruction, and pain in the tissue or organ affected and returns the tissue or organ to nearly normal functioning, while showing none of the side effects of previous treatments. Prolonged use of the anti-herpetic compounds reduces prodrome, vesicle formation and viral shedding. The anti-herpetic compounds may be administered alone or in combination with a compound that reduces the rate of renal excretion of the anti-herpetic compound. The anti-herpetic compounds are particularly useful when administered at a level equivalent in activity to 250 mg/kg famciclovir per day.

2011011, May 12, 2011

Mar 6, 2009

12/921006

Ray W Exley - Beverly Hills CA, US

A61K 31/522, A61P 25/00

51426338

Anti-herpetic material such as 2-aminopurine derivatives, e.g., the aminocyclopropylcarboxylate derivatives of acyclovir, penciclovir, and ganciclovir, are described to prevent or treat autoimmune disease or a disease originating from an abnormal functioning of the sympathetic chain in a human subject. Prolonged use of the anti-herpetic compounds reduces prodrome, vesicle formation and viral shedding. The anti-herpetic compounds may be administered alone or in combination with a compound that reduces the rate of renal excretion of the anti-herpetic compound. The anti-herpetic compounds are particularly useful when administered at a level equivalent in activity to at—least about 150 mg/kg famciclovir per day.

5559114, Sep 24, 1996

Dec 16, 1994

8/358335

Ray W. Exley - Beverly Hills CA

A61K 3152

514261

A method for treating autoimmune disease in a mammalian subject, particularly a human, which method comprises administering a therapeutically effective amount of certain 2-amino purine compounds to the subject. The compounds particularly useful are antiviral compounds exemplified by acyclovir, penciclovir and famciclovir. The compounds are administered at doses significantly higher than the dose level used to treat viral infections, e. g. , doses that will result in blood plasma levels of about 3-10 micrograms/mi.