Inventors:
ANATOLIY MARKIV - Brentford, GB
Ravi Venkata Durvasula - Albuquerque NM, US
Angray Singh Kang - Leyton, GB
International Classification:
A61K 49/00, C07H 21/00, C12N 5/09, C12N 1/00, C12P 21/02, C12Q 1/04, G01N 33/53, C12Q 1/02, G01N 33/543, C07K 19/00, C12N 15/85
US Classification:
424 96, 5303873, 536 234, 435325, 435243, 435455, 435 34, 435 71, 435 72, 435 29, 436501, 435 696
Abstract:
Embodiments of the present invention provide for the facile generation of a stable recombinant fusion polypeptides with intrinsic fluorescent properties. The recombinant antibodies may be suitable for qualitative and/or quantitative immunofluorescence analysis. Generally, the fluorescent polypeptides include a fluorescent domain comprising a C-terminus and an N-terminus; a first antibody domain covalently linked to the C-terminus; and a second antibody domain covalently linked to the N-terminus.