DR. RAO R. IVATURY, M.D.
Radiology at Marshall St, Richmond, VA

2013031, Nov 21, 2013

Jul 26, 2013

13/952186

Gary Bowlin - Mechanicsville VA, US
Kelman I. Cohen - Richmond VA, US
Kevin R. Ward - Glenn Allen VA, US
Wayne Barbee - Glenn Allen VA, US
Rao Ivatury - Richmond VA, US

Virginia Commonwealth University - Richmond VA

A61L 26/00

604319, 424445, 424 7835, 5263076

High-pressure bleeding wounds (and other bleeding wounds) may be treated by applying direct pressure directly in the bleeding wound, such as by applying a back pressure in a confined space around and in the wound. Certain substances and articles may be inserted into the wound, and the wound may be enclosed with that substance or article (such as a hemostatic substance, which may be polymeric), by swelling on contact with molecules (such as water molecules in the blood) encountered in the wound, generates the desired pressure to stop or at least reduce the bleeding without the detrimental effects of a tourniquet. Clot-inducing substances may be introduced into the wound contemporaneously with direct pressure application directly in the wound. Compressible and non-compressible wounds are treated. Treatment stops bleeding without producing pressure injury or ischemic damage. Medical devices using this technology are provided, including removable, biodegradable, medic-administrable devices.

7118534, Oct 10, 2006

Sep 21, 2001

10/380347

Kevin R. Ward - Glenn Allen VA, US
Robert W. Barbee - Richmond VA, US
Rao R. Ivatury - Richmond VA, US
Bruce D. Spiess - Manakin-Sabot VA, US
James A. Arrowood - Richmond VA, US

Virginia Commonwealth University - Richmond VA

A61B 5/02

600490, 600500, 600485

Central Venous Pressure (CVP) is non-invasively determined with accuracy comparable to invasive measurement techniques. To do so, curves are plotted based on non-invasively determined patient information obtained by applying a controllable variable (pressure) to a vein of interest at a non-distal point and taking certain measurements (such as pressure and volume measurements) from the patient. An example of a controllable variable is voltage applied in incremental inflation/deflation of a vascular cuff (). A curve is plotted based on datapoints (such as a volume increase curve or a volume decline curve). Pertinent, accurate CVP and/or blood volume information is obtained from the slope of the non-invasive-based curve. Accurate CVP information is provided without the risks and disadvantages of invasive measurements.

2004001, Jan 22, 2004

Aug 13, 2003

10/363994

Gary Wnek - Midlothian VA, US
Marcus Carr - Richmond VA, US
Gary Bowlin - Mechanicsville VA, US
Kelman Cohen - Richmond VA, US
Kevin Ward - Glenn Allen VA, US
Wayne Barbee - Glen Allen VA, US
Rao Ivatury - Richmond VA, US

A61L015/00, A61K009/70

424/445000, 424/443000

High-pressure bleeding wounds (and other bleeding wounds) may be treated by applying direct pressure directly in the bleeding wound, such as by applying a back pressure in a confined space around and in the wound. Certain substances and articles may be inserted into the wound, and the wound may be enclosed with that substance or article (such as a hemostatic substance, which may be polymeric), by swelling on contact with molecules (such as water molecules in the blood) encountered in the wound, generates the desired pressure to stop or at least reduce the bleeding without the detrimental effects of a tourniquet Clot-inducing substances may be introduced into the wound contemporaneously with direct pressure application directly in the wound. Compressible and non-compressible wounds are treated. Treatment stops bleeding without producing pressure injury or ischemic damage. Medical devices using this technology are provided, including removable, biodegradable, medic-administrable devices.

2004003, Feb 26, 2004

Jul 29, 2003

10/332613

Kevin Ward - Glen Allen VA, US
R. Barbee - Richmond VA, US
James Terner - Richmond VA, US
Rao Ivatury - Richmond VA, US
Fred Hawkridge - Glen Allen VA, US

A61B005/00

600/312000

In an emergency medicine patient, accurate measurement of change or lack thereof from non-shock, non-ischemic, non-inflammation, non-tissue injury, non-immune dysfunction conditions is important and is provided, as practical, real-time approaches for accurately characterizing a patient's condition, using Raman () and/or fluorescence () spectroscopy with a high degree of accuracy. Measurement times are on the order of seconds. High-accuracy measurement is achieved with Raman spectroscopy interrogation of tissue. Simultaneous interrogation by NADH fluorescence spectroscopy may he used. Measurements may be non-invasive to minimally invasive. Preclinical (ultra-early) states of shock can be detected (), severity can be determined, effectiveness of various treatments can be determined.

8497408, Jul 30, 2013

Sep 14, 2007

11/855205

Gary Wnek - Midlothian VA, US
Gary Bowlin - Mechanicsville VA, US
Kelman I. Cohen - Richmond VA, US
Kevin R. Ward - Glenn Allen VA, US
Wayne Barbee - Glen Allen VA, US
Rao Ivatury - Richmond VA, US

Virginia Commonwealth University - Richmond VA

A61F 13/00

602 56, 602 42, 602 48, 602 53, 602 58

High-pressure bleeding wounds (and other bleeding wounds) may be treated by applying direct pressure directly in the bleeding wound, such as by applying a back pressure in a confined space around and in the wound. Certain substances and articles may be inserted into the wound, and the wound may be enclosed with that substance or article (such as a hemostatic substance, which may be polymeric), by swelling on contact with molecules (such as water molecules in the blood) encountered in the wound, generates the desired pressure to stop or at least reduce the bleeding without the detrimental effects of a tourniquet. Clot-inducing substances may be introduced into the wound contemporaneously with direct pressure application directly in the wound. Compressible and non-compressible wounds are treated. Treatment stops bleeding without producing pressure injury or ischemic damage.

8042544, Oct 25, 2011

Sep 2, 2005

11/217667

Kevin R. Ward - Glenn Allen VA, US
Curtis N. Sessler - Richmond VA, US
Mary Jo Grap - Midlothian VA, US
Laurence J. Dinardo - Richmond VA, US
Bruce D. Spiess - Manakin Sabot VA, US
Rao R. Ivatury - Richmond VA, US
Cindy Munro - Richmond VA, US

Virginia Commonwealth University - Richmond VA

A61M 16/00

12820714, 12820715

Ventilator associated pneumonia (VAP) may be prevented in a patient, or its occurrence reduced in a population of patients, by disposing in a patient airway an anti-VAP device or an anti-VAP material. By reducing the problem of bacterial-containing secretions that otherwise build up in the airway of the intubated patient, VAP can be prevented from occurring in intubated patients, such as patients intubated with an endotracheal tube (ETT) or a nasogastric tube.