Inventors:
Cornelis J. Van der Schyf - Akron OH, US
Randolph B. Schiffer - Lubbock TX, US
Paula Grammas - Lubbock TX, US
Masao Roy Wilson - Denver CO, US
Werner J. Geldenhuys - Kent OH, US
Assignee:
NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE - Rootstown OH
International Classification:
C07D 209/56, A61K 31/403, A61P 27/02
Abstract:
Described herein are various compounds for treatment of ocular neurodegenerative diseases, including but not limited to glaucoma and diabetic retinopathy. The compounds described herein can act to attenuate and/or block calcium release from external neuronal environments as well as intracellular stores.