Inventors:
Arwinder S. Nagi - Thiells NY, US
Ramarao Chatlapalli - Hopewell Junction NY, US
Shamim Hasan - East Elmhurst NY, US
Rolland W. Carson - Middletown NY, US
Mohamed Ghorab - Edison NJ, US
International Classification:
A61K 31/535
US Classification:
5142305, 514170, 544 70, 544 92
Abstract:
Compositions, preferably pharmaceutical compositions, containing micronized tanaproget, or pharmaceutically acceptable salt thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, butylated hydroxyanisole, povidone, and magnesium stearate, are provided. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefor. Additional uses include stimulation of food intake.