RAM K MENON
Medical Practice in Pittsburgh, PA
License number
Pennsylvania LT000143L
Category
Medicine
Type
Institutional License
Address
Address
Pittsburgh, PA 15217
Personal information
See more information about RAM K MENON at radaris.comName
Address
Phone
5450 Guarino Rd, Squirrel Hill, PA 15217
Professional information
Method Of Restoring Ciliated Cell Motility
US Patent:
2003022, Dec 11, 2003
Filed:
Sep 28, 2001
Appl. No.:
09/967399
Inventors:
Ram Menon - Pittsburgh PA, US
Mark Sperling - Pittsburgh PA, US
Chunxia Lu - Pittsburgh PA, US
Selma Witchel - Pittsburgh PA, US
John Kasik - Santa Maria CA, US
Mark Sperling - Pittsburgh PA, US
Chunxia Lu - Pittsburgh PA, US
Selma Witchel - Pittsburgh PA, US
John Kasik - Santa Maria CA, US
International Classification:
A61K048/00
US Classification:
514/044000, 800/021000
Abstract:
The present invention relates to a novel gene from the insulin family, Insl6, which expresses a protein restoring motility in ciliated cells. The proteins of the insulin family play essential roles in pleiotropic physiological processes affecting metabolism, growth, and reproduction. A new member of the insulin family named Insl6 is disclosed playing an essential role in ciliated cell activity. Insl6 plays an essential role in spermatocyte function. Thus, the Insl6 gene and its protein product are useful in the treatment of infertility caused by the loss of spermatocyte motility. A method of modulating male fertility is disclosed.