DR. RALPH V SHOHET, M.D.
Medical Practice at Punchbowl St, Honolulu, HI
License number
Hawaii MD13726
Category
Medical Practice
Type
Specialist
Address
Address
1301 Punchbowl St, Honolulu, HI 96813
Phone
(808) 586-7476
(808) 586-7486 (Fax)
(808) 537-3422
(808) 535-5976 (Fax)
(808) 586-7486 (Fax)
(808) 537-3422
(808) 535-5976 (Fax)
Organization information
See more information about RALPH V SHOHET at bizstanding.comRalph V Shohet MD
1301 Punchbowl St, Honolulu, HI 96813
Categories:
Cardiology Physicians & Surgeons, Medical Research & Development
Phone:
(808) 692-1469 (Phone)
Ralph V Shohet MD
651 Ilalo St, Honolulu, HI 96813
Categories:
Cardiology Physicians & Surgeons
Phone:
(808) 692-1080 (Phone)
Professional information
Dr. Ralph V Shohet, Honolulu HI - MD (Doctor of Medicine)
Specialties:
Cardiology
Address:
1301 Punchbowl St, Honolulu 96813
(808) 586-7476 (Phone), (808) 586-7486 (Fax)
(808) 586-7476 (Phone), (808) 586-7486 (Fax)
Conditions:
Arrhythmias (incl. Atrial Fibrillation), Coronary Artery Disease (CAD), Heart Attack (Acute Myocardial Infarction), Hypertension, Hypertensive Heart Disease
Certifications:
Cardiovascular Disease, 2001, Internal Medicine, 1986
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
1301 Punchbowl St, Honolulu 96813
The Queens Medical Center
1301 Punchbowl St, Honolulu 96813
The Queens Medical Center
1301 Punchbowl St, Honolulu 96813
Education:
Medical School
University of California At San Diego
Graduated: 1983
Parkland Memorial Hospital
Nih; Utsw
University of California At San Diego
Graduated: 1983
Parkland Memorial Hospital
Nih; Utsw
Ralph V Shohet, Honolulu HI
Specialties:
Internal Medicine, Cardiovascular Disease
Work:
Queen Emma Clinics
1301 Punchbowl St, Honolulu, HI 96813
1301 Punchbowl St, Honolulu, HI 96813
Education:
University of California at San Diego (1983)
Methods And Compositions For Targeted Delivery Of Gene Therapeutic Vectors
US Patent:
2011013, Jun 2, 2011
Filed:
May 3, 2008
Appl. No.:
12/517520
Inventors:
Stefan Moisyadi - Honolulu HI, US
Ralph V. Shohet - Honolulu HI, US
Joseph M. Kaminski - Bethesda MD, US
Ralph V. Shohet - Honolulu HI, US
Joseph M. Kaminski - Bethesda MD, US
International Classification:
A61K 31/711, A61P 43/00
US Classification:
514 44 R
Abstract:
Embodiments of the present invention relate to methods and compositions for tissue- specific delivery of a gene therapeutic, transgenic nucleic acid in mammals. Methods and compositions of the invention include the steps of providing a nucleic acid comprising a transgene flanked by two terminal repeats and, within the same or on a separate nucleic acid, a nucleotide sequence encoding a transposase, wherein the transgene comprises a biotherapeutic gene, contacting the nucleic acid with perfluorocarbon gas-filled microbubbles to form a mixture, introducing the mixture into the bloodstream of a mammal, and focusing ultrasound pulses on a specific tissue of said mammal, wherein said pulses disrupt said microbubbles of said mixture and release said nucleic acid into the bloodstream within the target tissue, thereby enabling uptake of the transgenic nucleic acid into the cells of said target tissue.