Inventors:
Jeffry Dean Watkins - Encinitas CA, US
Alain P. Vasserot - Carlsbad CA, US
Rajesh Belani - San Diego CA, US
Leslie Ann Greene - San Diego CA, US
Ryan Andrew Adams - San Diego CA, US
Assignee:
ATYR PHARMA, INC. - San Diego CA
International Classification:
A61K 39/395, A61K 38/53, C12N 5/078, A61K 35/12, C07H 21/00, C12N 15/63, C12N 5/10, C12N 9/00, C07K 16/18, C07K 14/00, A61P 7/00
US Classification:
4241391, 424 945, 435377, 424 937, 536 232, 4353201, 435325, 435183, 5303879, 530300
Abstract:
Hematopoietic-modulating compositions are provided comprising aminoacyl-tRNA synthetase polypeptides, including active fragments and/or variants thereof, as well as compositions comprising related agents such as antibodies and other binding agents. Also provided are methods of using such compositions in the treatment of conditions that benefit from the modulation of hematopoiesis.