PROSPER BENHAIM, MD
Medical Practice at Le Conte Ave, Los Angeles, CA

6777231, Aug 17, 2004

Sep 10, 2001

09/936665

Adam J. Katz - Charlottesville VA
Ramon Llull - Mallorca, ES
William J. Futrell - Pittsburgh PA
Marc H. Hedrick - Encino CA
Prosper Benhaim - Los Angeles CA
Hermann Peter Lorenz - Los Angeles CA
Min Zhu - Los Angeles CA

The Regents of the University of California - Oakland CA

C12N 500

435325, 435366

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.

2004017, Sep 2, 2004

Mar 9, 2004

10/797371

Adam Katz - Charlottesville VA, US
Ramon Llull - Santa Maria - Mallorca, ES
J. Futrell - Pittsburgh PA, US
Marc Hedrick - Encino CA, US
Prosper Benhaim - Los Angeles CA, US
Hermann Lorenz - Los Angeles CA, US
Min Zhu - Los Angeles CA, US

C12N005/08

435/366000, 435/368000, 435/372000

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.

2005028, Dec 22, 2005

Aug 24, 2005

11/211114

Adam Katz - Charlottesville VA, US
Ramon Llull - Santa Maria-Mallorca, ES
J. Futrell - Pittsburgh PA, US
Marc Hedrick - Encino CA, US
Prosper Benhaim - Los Angeles CA, US
Hermann Lorenz - Los Angeles CA, US
Min Zhu - Los Angeles CA, US

University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
The Regents of the University of California - Oakland CA

C12N005/08

435366000

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The invention also provides a method of isolating stem cells from adipose tissues. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.

2002007, Jun 20, 2002

Sep 6, 2001

09/947985

Adam Katz - Charlottesville VA, US
Ramon Llull - Mallorca, ES
J. Futrell - Pittsburgh PA, US
Marc Hedrick - Encino CA, US
Prosper Benhaim - Los Angeles CA, US
Hermann Lorenz - Los Angeles CA, US
Min Zhu - Los Angeles CA, US

University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA

A61K048/00, C12N005/08, A61K038/19

424/093210, 435/366000, 435/455000, 424/085100

The present invention provides adipose-derived stem cells and lattices. In one aspect, the present invention provides a lipo-derived stem cell substantially free of adipocytes and red blood cells and clonal populations of connective tissue stem cells. The invention also provides a method of isolating stem cells from adipose tissues. The cells can be employed, alone or within biologically-compatible compositions, to generate differentiated tissues and structures, both in vivo and in vitro. Additionally, the cells can be expanded and cultured to produce hormones and to provide conditioned culture media for supporting the growth and expansion of other cell populations. In another aspect, the present invention provides a lipo-derived lattice substantially devoid of cells, which includes extracellular matrix material from adipose tissue. The lattice can be used as a substrate to facilitate the growth and differentiation of cells, whether in vivo or in vitro, into anlagen or even mature tissues or structures.