PROF. PIERLUIGI GAMBETTI, M.D.
Medical Practice in Cleveland, OH
License number
Ohio 35.041888
Category
Medical Practice
Type
Research Study
Address
Address
2085 Case Western Reserve University ROOM 419, Cleveland, OH 44106
Phone
(216) 368-0587
(216) 368-2546 (Fax)
(216) 921-8735
(216) 491-8037 (Fax)
(216) 368-2546 (Fax)
(216) 921-8735
(216) 491-8037 (Fax)
Personal information
See more information about PIERLUIGI GAMBETTI at radaris.comName
Address
Phone
2949 Broxton Rd, Shaker Heights, OH 44120
Cleveland, OH
2949 Broxton Rd, Cleveland, OH 44120
Professional information
See more information about PIERLUIGI GAMBETTI at trustoria.com
Pierluigi Gambetti, Cleveland OH
Pierluigi Gambetti, Cleveland OH
Specialties:
Pathology, Neuropathology, Anatomic Pathology
Work:
Institute Of Pathology
2085 Adelbert Rd, Cleveland, OH 44106 University Hospitals of Cleveland
11100 Euclid Ave, Cleveland, OH 44106
2085 Adelbert Rd, Cleveland, OH 44106 University Hospitals of Cleveland
11100 Euclid Ave, Cleveland, OH 44106
Education:
Universita Degli Studi Di Bologna (1959)
Dr. Pierluigi Gambetti, Cleveland OH - MD (Doctor of Medicine)
Dr. Pierluigi Gambetti, Cleveland OH - MD (Doctor of Medicine)
Specialties:
Neuropathology
Address:
University Hospital Pathology
11100 Euclid Ave, Cleveland 44106
(216) 844-1807 (Phone)
11100 Euclid Ave, Cleveland 44106
(216) 844-1807 (Phone)
Certifications:
Neuropathology, 1981
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
University of Bologna / Faculty of Medicine And Surgery
University of Bologna / Faculty of Medicine And Surgery
Immunological Agents Specific For Prion Protein (Prp)
Immunological Agents Specific For Prion Protein (Prp)
US Patent:
6528269, Mar 4, 2003
Filed:
Dec 3, 1998
Appl. No.:
09/204816
Inventors:
Man-Sun Sy - Shaker Heights OH
Pierluigi Gambetti - Shaker Heights OH
Pierluigi Gambetti - Shaker Heights OH
Assignee:
Case Western Reserve University - Cleveland OH
International Classification:
G01N 3353
US Classification:
435 71, 424 91, 4241301, 4241331, 4241341, 4241371, 4241381, 4241391, 4241411, 4241451, 436501, 436513, 436536, 436547
Abstract:
The present invention is directed to a panel of monoclonal antibodies (Mabs) specific for murine prion protein PrP. These Mabs can be applied to immunoblotting, cell surface immunofluorescent staining and immunohistochemistry at light and electron microscopy. Additionally, these Mabs recognize both the normal (PrP ) and protease-resistant (PrP ) isoforms of PrP. Some Mabs are species restricted, while others react with PrP from a broad range of mammals including mice, humans, monkeys, cows, sheep, squirrels and hamsters. Moreover, several of the Mabs selectively recognize different PrP glycoforms as well as the metabolic fragments of PrP. These newly generated PrP antibodies are useful for exploring the biology of PrP and to establish the diagnosis of prion diseases in both humans and animals.