Phyllis W Ying
Pharmacy at Bell Dr, Morristown, NJ

License number
DC PHA22395
Issued Date
Jan 3, 1974
Expiration Date
Feb 28, 2019
Category
PHARMACY - PROFESSIONAL
Type
PHARMACIST
Address
Address
5 Bell Dr, Morristown, NJ 07960

Professional information

Phyllis Ying Photo 1

Dual Control Sustained Release Drug Delivery Systems And Methods For Preparing Same

US Patent:
5656296, Aug 12, 1997
Filed:
Jun 7, 1995
Appl. No.:
8/476490
Inventors:
Sadath U. Khan - Randolph NJ
Phyllis Ying - Morristown NJ
Russell U. Nesbitt - Somerville NJ
Mahdi B. Fawzi - Flanders NJ
Jay Weiss - East Brunswick NJ
Assignee:
Warner-Lambert Company - Morris Plains NJ
International Classification:
A61K 924
US Classification:
424473
Abstract:
The present invention pertains to a dual control sustained release drug delivery system which comprises a core and a porous coating layer over the core, wherein the coated core comprises (A) a core comprising in percentages by weight of the core composition (a) a medicament present in an amount from about 60% to about 90%; (b) an edible material having a melting point from about 25. degree. C. to about 100. degree. C. selected from the group consisting of (i) fatty acids having an iodine value from about 1 to about 10, (ii) natural waxes, (iii) synthetic waxes, and (iv) mixtures thereof, present in an amount from about 5% to about 40%; and (B) a porous coating layer over the core comprising in percentages by weight of the coating layer composition (a) a pH-independent water-insoluble polymer present in an amount from about 40% to about 80%; and (b) a water-soluble film forming polymer present in an amount from about 20% to about 60%.

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