PHYLLIS I. GARDNER, MD
Osteopathic Medicine at Pasteur Dr, Palo Alto, CA
License number
California G39477
Category
Osteopathic Medicine
Type
Internal Medicine
Address
Address
300 Pasteur Dr, Palo Alto, CA 94305
Phone
(650) 723-4000
Professional information
Prolonged Release Active Agent Dosage Form Adapted For Gastric Retention
US Patent:
6548083, Apr 15, 2003
Filed:
Jul 13, 2000
Appl. No.:
09/615110
Inventors:
Patrick S.-L. Wong - Burlingame CA
David E. Edgren - El Granada CA
Felix Theeuwes - Los Altos CA
Phyllis I. Gardner - Stanford CA
Francisco Jao - San Jose CA
Jason J. Wan - Palo Alto CA
David E. Edgren - El Granada CA
Felix Theeuwes - Los Altos CA
Phyllis I. Gardner - Stanford CA
Francisco Jao - San Jose CA
Jason J. Wan - Palo Alto CA
Assignee:
Alza Corporation - Mountain View CA
International Classification:
A61K 922
US Classification:
424473, 424468, 424469, 424470, 424486, 424488, 514781, 514782, 514784
Abstract:
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
Prolonged Release Active Agent Dosage Form Adapted For Gastric Retention
US Patent:
6120803, Sep 19, 2000
Filed:
Aug 10, 1998
Appl. No.:
9/131923
Inventors:
Patrick S. L. Wong - Burlingame CA
David E. Edgren - El Granada CA
Felix Theeuwes - Los Altos CA
Phyllis I. Gardner - Stanford CA
Francisco Jao - San Jose CA
Jason J. Wan - Palo Alto CA
David E. Edgren - El Granada CA
Felix Theeuwes - Los Altos CA
Phyllis I. Gardner - Stanford CA
Francisco Jao - San Jose CA
Jason J. Wan - Palo Alto CA
Assignee:
ALZA Corporation - Mountain View CA
International Classification:
A61K 922, A61K 926
US Classification:
424473
Abstract:
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a polymer matrix that swells upon contact with the fluids of the stomach. A portion of the polymer matrix is surrounded by a band of insoluble material that prevents the covered portion of the polymer matrix from swelling and provides a segment of the dosage form that is of sufficient rigidity to withstand the contractions of the stomach and delay expulsion of the dosage form from the stomach until substantially all of the active agent has been dispensed.
Phyllis Irene Gardner, Stanford CA
Specialties:
Internal Medicine, Clinical Pharmacology
Work:
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford, CA 94305 SHC
300 Pasteur Dr, Palo Alto, CA 94304
300 Pasteur Dr, Stanford, CA 94305 SHC
300 Pasteur Dr, Palo Alto, CA 94304
Education:
Harvard University(1976)
Dr. Phyllis I Gardner, Stanford CA - MD (Doctor of Medicine)
Specialties:
Internal Medicine
Address:
300 Pasteur Dr STE A200, Stanford 94305
(650) 498-4826 (Phone), (650) 724-7778 (Fax)
(650) 498-4826 (Phone), (650) 724-7778 (Fax)
Certifications:
Internal Medicine, 1980
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
300 Pasteur Dr STE A200, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Stanford Hospital and Clinics
300 Pasteur Dr, Stanford 94305
Education:
Medical School
Harvard Medical School
Graduated: 1976
Massachusetts General Hospital
Stanford Med Ctr
Harvard Medical School
Graduated: 1976
Massachusetts General Hospital
Stanford Med Ctr
Methods And Compositions For Determining Whether A Subject Carries A Disease Associated Gene Mutation Common In Jewish Populations
US Patent:
2010030, Dec 2, 2010
Filed:
Oct 25, 2007
Appl. No.:
11/916439
Inventors:
Iris Schrijver - Woodside CA, US
Phyllis Gardner - Stanford CA, US
Eugene Pergament - Chicago IL, US
Morry Fiddler - Chicago IL, US
Phyllis Gardner - Stanford CA, US
Eugene Pergament - Chicago IL, US
Morry Fiddler - Chicago IL, US
Assignee:
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY - Palo Alto CA
International Classification:
C40B 30/04, C40B 40/06
US Classification:
506 9, 506 16
Abstract:
Methods are provided for determining whether a subject carries a disease associated gene mutation common in Jewish populations. In practicing the subject methods, an array comprising a plurality of associated gene mutation probes is contacted with a nucleic acid sample from the subject, and the presence of any resultant surface bound target nucleic acids is detected to determine whether the subject carries an disease associated gene mutation common in Jewish populations. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
Methods And Compositions For Determining Whether A Subject Carries A Gene Mutation Associated With Hereditary Hearing Loss
US Patent:
2007013, Jun 14, 2007
Filed:
Nov 14, 2006
Appl. No.:
11/559575
Inventors:
IRIS SCHRIJVER - San Jose CA, US
PHYLLIS GARDNER - Stanford CA, US
ENELI OITMAA - Tartumae, EE
PHYLLIS GARDNER - Stanford CA, US
ENELI OITMAA - Tartumae, EE
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
Methods are provided for determining whether a subject carries a gene mutation associated with Hereditary Hearing Loss (HHL). In practicing the subject methods, an array comprising a plurality of HHL-associated gene mutation probes is contacted with a nucleic acid sample from the subject, and the presence of any resultant surface bound target nucleic acids is detected to determine whether the subject carries a HHL-associated gene mutation. In addition, reagents and kits thereof that find use in practicing the subject methods are provided.
Oral Delivery Of Discrete Units
US Patent:
5780058, Jul 14, 1998
Filed:
Jul 19, 1996
Appl. No.:
8/684602
Inventors:
Patrick S.-L. Wong - Palo Alto CA
Howard B. Rosen - Los Gatos CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Howard B. Rosen - Los Gatos CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Assignee:
ALZA Corporation - Palo Alto CA
International Classification:
A61K 924
US Classification:
424473
Abstract:
The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber (10) containing the active agent formulation and having a fluid passing active agent formulation retainer (14) is placed at one end (16) into a fluid and at a second end (18) into a patient's mouth. The active agent is delivered when the patient sips on the end of the chamber.
Oral Delivery Of Discrete Units
US Patent:
6210713, Apr 3, 2001
Filed:
Feb 25, 2000
Appl. No.:
9/513074
Inventors:
Patrick S.-L. Wong - Burlingame CA
Howard B. Rosen - Woodside CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Howard B. Rosen - Woodside CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Assignee:
Alza Corporation - Palo Alto CA
International Classification:
A61K 914, A61K 924
US Classification:
424473
Abstract:
The present invention is an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.
Oral Delivery Of Discrete Units
US Patent:
6333050, Dec 25, 2001
Filed:
Jan 19, 2001
Appl. No.:
9/764074
Inventors:
Patrick S.-L. Wong - Burlingame CA
Howard B. Rosen - Woodside CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Howard B. Rosen - Woodside CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Assignee:
Alza Corporation - Palo Alto CA
International Classification:
A61K 914, A61K 924
US Classification:
424473
Abstract:
The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.
Oral Delivery Of Discrete Units
US Patent:
6106845, Aug 22, 2000
Filed:
Apr 27, 1999
Appl. No.:
9/299740
Inventors:
Howard B. Rosen - Los Gatos CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Nathan Roth - San Francisco CA
Phyllis I. Gardner - Stanford CA
Assignee:
ALZA Corporation - Mountain View CA
International Classification:
A61K 900, A61K 924
US Classification:
424400
Abstract:
The present invention is directed to an oral active agent delivery system and method for delivering discrete units of an active agent formulation to a patient. An active agent formulation chamber containing the active agent formulation and having a fluid passing active agent formulation retainer is placed at a first end into a fluid and at a second end into a patient's mouth. The active agent is delivered when the patient sips on the second end of the chamber.