Inventors:
Lawrence B. Sandberg - Colton CA
Philip J. Roos - Loma Linda CA
Thomas F. Mitts - Visalia CA
International Classification:
A61K 3801, A61K 3808
Abstract:
The present invention is directed to a formulation or composition which is used to enhance the softness, elastin, or appearance of tissue by increasing the endogenous elastin production. Specifically, the present invention is directed to a composition formulated from the products of thermolysin digestion which are filtered through a 10,000 molecular weight cutoff device, which may be dried to have a formulation which contains 90% or greater of peptides having a molecular weight lower than 10,000 Da. This formulation is preferably applied to human skin in a cosmetic or therapeutic formulation and results in enhanced elasticity of the skin.