Inventors:
Gary Gerstenblith - Reisterstown MD, US
Jason Benkoski - Ellicott City MD, US
Jeffrey Brinker - Baltimore MD, US
George Coles - Baltimore MD, US
Chao-Wei Hwang - Ellicott City MD, US
Peter Johnston - Baltimore MD, US
Gordon Tomaselli - Lutherville MD, US
Robert G. Weiss - Hunt Valley MD, US
Steven P. Schulman - Reisterstown MD, US
Assignee:
The Johns Hopkins University - Baltimore MD
International Classification:
A61M 5/00
Abstract:
An implantable bioreactor containing a barrier which is designed to allow the release of cell-derived biomolecules, but restricts the entry of immunologic and other cells, or the egress of the cells contained within the bioreactor. Two broad classes of implantable bioreactors are envisioned, encompassing devices for both systemic delivery of the bio-products and local delivery at the target tissue. Bioreactors of both classes can be implanted via surgery, through percutaneous techniques, or other techniques which effect implantation.