PETER THOMAS PUGLIESE
Medical Practice in New Schaefferstown, PA

8236333, Aug 7, 2012

Jun 25, 2009

12/491903

Raymond J. Tarasi - Pittsburgh PA, US
Gary W. Dalrymple - Allison Park PA, US
Peter Pugliese - Bernville PA, US
Steven M. Pugliese - Bernville PA, US

UNIREM, Inc. - Pittsburgh PA

A61K 9/50, A61K 47/44, A61Q 5/00, A61Q 19/00

424401, 424451, 424502, 514787, 510119, 510130

An active agent delivery and/or odor retentive composition including a surfactant and wax spheres formed from at least one of beeswax and soy wax and methods of use thereof. The composition is particularly useful in the cosmetics and medical industry for delivering/carrying a particular ingredient to one's skin, scalp or hair; for absorbing odor causing materials, such as fuel byproducts from a skin surface; and/or for providing exfoliating properties to the skin. The delivery system/carrying system is also useful in binding to certain nutritional materials, such as vitamins, minerals, antioxidants, and the like for ingestion and release into the body.

8609119, Dec 17, 2013

Jul 11, 2012

13/546369

Raymond J. Tarasi - Pittsburgh PA, US
Gary W. Dalrymple - Allison Park PA, US
Peter Pugliese - Bernville PA, US
Steven M. Pugliese - Bernville PA, US

UNIREM, Inc. - Pittsburgh PA

A61K 9/50, A61K 47/44, A61Q 5/00, A61Q 19/00

424401, 424451, 424502, 514787, 510119, 510130

An active agent delivery and/or odor retentive composition including a surfactant and wax spheres formed from at least one of beeswax and soy wax and methods of use thereof. The composition is particularly useful in the cosmetics and medical industry for delivering/carrying a particular ingredient to one's skin, scalp or hair; for absorbing odor causing materials, such as fuel byproducts from a skin surface; and/or for providing exfoliating properties to the skin. The delivery system/carrying system is also useful in binding to certain nutritional materials, such as vitamins, minerals, antioxidants, and the like for ingestion and release into the body.

6497892, Dec 24, 2002

Oct 18, 2001

09/978597

Peter T. Pugliese - Bernville PA 17901
Steven M. Pugliese - Bernville PA 17901

A61K 700

424401, 424 7012, 424400, 514566

A hair and scalp formulation based on a peroxidase enzyme and synergistic yeast extract therefore. It entails a chemically-inert carrier material, a germicidal/preservative agent, and a metal chelating agent. A skin protective formulation based on peroxidase enzyme and yeast extract. It entails a polymer carrier, a fatty acid emollient, a co-emulsifier of an amino acid complex essential to a fatty acid; an emulsifying agent; a skin healing agent, and a germicidal surfactant. An aqueous formulation adapted for topical hair rinsing consisting of a peroxidase enzyme, a yeast extract adapted to enhance the activity of the enzyme and a cationic hair conditioning agent selected from water-soluble thickening resins.

2004007, Apr 15, 2004

Jun 3, 2003

10/454744

W. Church - Tampa FL, US
Randall Krafft - Tampa FL, US
Peter Pugliese - Bernville PA, US
Peter Pugliese - Bethel PA, US

A61N001/00

607/001000

A body tissue treatment system comprising a heating device and a topical cream comprises controlled, non-burning heat exhibiting greater temperature fluctuation than a conventional heating device. At high temperature settings, the heating elements fluctuate widely between a relatively high maximum and low minimum to produce periods of intense heat input into the skin followed by sufficient cooling to prevent burning of the skin. Such application of intense heat to the skin, for short periods in which temperatures reach their peaks, relaxes musculature surrounding the injured area and significantly improves blood flow, skin permeability, and sweat gland openness in the area, which allows the topical cream to more readily penetrate skin and/or injured body tissues. While the skin temperature rises and falls to some extent in response to the heating device, the intense heating periods are believed to cause such high blood flow and consequent heat transfer away from the skin surface that the skin temperature does not rise to the extent of being damaged or burned.

6153207, Nov 28, 2000

Mar 5, 1998

9/035315

Peter T. Pugliese - Bernville PA

A01N 2534

424402

A garment for treating the skin, a method of making the garment and a method of using the garment to treat the skin, made of garment material, in particular hose material to be worn tightly against the skin, which has a multiplicity of durable chemical bonding sites. The durable sites which are preferably of the type to make covalent bonds, are bound to binding molecules which form chemical hooks for the garment material. Each of the chemical hooks has one or more semi-durable chemical bonding sites of the type which can chemically bond an active ingredient molecule to the binding agent but which is broken in the presence of skin conditions which are normal such as normal skin pH, normal skin moisture and normal skin heat generated both by body heat and the heat of friction of the garment rubbing against the skin. Active ingredient molecules such as molecules of theophylline or theophylline complexes are bound to the binding agent and are released to the skin when the garment is worn.

4398541, Aug 16, 1983

May 25, 1978

5/909664

Peter Pugliese - Bernville PA

Xienta, Inc. - Bernville PA

A61B 500

128665

There are disclosed a method and an apparatus for measuring moisture content of skin. The skin surface is illuminated with polarized light incident at the Brewster angle. The degree of polarization of the light refracted within the skin and reflected out is measured. The measurement is a function of the refractive index of the skin which, in turn, is a function of the moisture content. To avoid measurement variations due to such things as skin color, output readings are in the form of a ratio of the reflected polarized light intensity to the reflected total light intensity.

5622690, Apr 22, 1997

Oct 29, 1993

8/145328

Richard Potter - Seeley Lake MT
Peter T. Pugliese - Bernville PA

Nurture, Inc. - Missoula MT

A61K 742

424 59

A composition comprising a seed-derived proteinaceous particulate material for reducing the formation of sunburn cells in skin exposed to ultraviolet irradiation and method of using same, where the seed-derived material has a protein content of between about 1% and 50% and an average particle size of between about 1. 0. mu. m and about 600. mu. m. Seed-derived proteinaceous particulate material is applied to skin in a topically acceptable carrier and reduces the formation of sunburn cells upon exposure of the skin to ultraviolet irradiation.

4750496, Jun 14, 1988

Jan 28, 1987

7/007776

Richard Reinhart - Lawrenceville NJ
Fred Letterio - Philadelphia PA
Peter Pugliese - Bernville PA
Carl Ritter - Aldan PA
Glenn Lubrano - Metairie LA
Jerry Guilbault - Slidell LA
Christopher Feistel - Laguna Beach CA

Xienta, Inc. - Bernville PA

A61B 500

128635

A non-invasive method for measuring blood glucose concentration using glucose present at the mucosal surface of a living being is provided. The method includes the steps of positioning a glucose oxidase membrane on the mucosal surface, providing oxygen for peroxidative oxidation of the glucose present thereat, electrically measuring the amount of hydrogen peroxide product and calibrating that amount to determine blood glucose concentration. Also provided are electrode devices suitable for carrying out the method.

4071020, Jan 31, 1978

Jun 3, 1976

5/692511

Peter Pugliese - Bernville PA

Xienta, Inc. - Bernville PA

A61B 500, A61B 1000, G01N 3316, G01T 1161

128 2A

There are disclosed apparatus and methods for performing in-vivo measurements of enzyme kinetics on the epidermis and mucous membranes of a subject. One or more reactants are placed on a predetermined area of the skin in order to react with the enzyme or other biological substance of interest. At least one physical characteristic of one or more of the reaction products formed is measured. Changes in enzymatic or related activity in response to various stimuli can be observed by continuously monitoring the physical characteristic of the reaction product while certain controls are varied, thereby providing dynamic information not previously obtainable.

4049830, Sep 20, 1977

Nov 6, 1975

5/629222

Peter T. Pugliese - Bernville PA

Milmark Research, Inc. - Bernville PA

A01N 924, A61K 31045, A61L 1300

424343

A bovine teat dip effective against both gram-positive and gram-negative bacteria, and containing lipids capable of reestablishing the natural lipid barrier or of forming a protective lipid barrier to foreign matter in the treated zone so as to minimize disruption of the natural defense mechanisms against infection or irritation.