Inventors:
Mark L. Nelson - Sommerville MA
Peter H. Doukas - Newtown PA
Leon Salganicoff - Philadelphia PA
Fiore J. Ricciardi - Milwaukee WI
Assignee:
Temple University of the Commonwealth System of Higher Education - Philadelphia PA
International Classification:
A61K 31495, A61K 31335, C07D24112
Abstract:
Novel 2-substituted trimethylpyrazine derivatives of the formula: ##STR1## wherein R is alkylamino, 4-methyl-1-piperazinyl, piperidino, morpholino or 2-trimethylpyrazinepropenyl.
These novel 2-substituted trimethylpyrazine derivatives exhibit, at very low concentrations, activity as inhibitors of platelet function and as promoters of blood pressure reduction.