Inventors:
Thomas Adkins - Austinburg OH, US
Charles Cicco - Cleveland Heights OH, US
Penina Feibush - Ambler PA, US
Donald Koch - Painesville OH, US
Cynthia Maryanoff - New Hope PA, US
Walter Stalzer - Mentor OH, US
International Classification:
C07D493/02, C07D317/44
US Classification:
549/396000, 549/417000, 549/440000, 558/047000
Abstract:
The present invention is directed to a continuous process for the preparation of fructopyranose sulfamate derivatives of the general formula (I)
wherein R, R, R, R, Rand X are as herein defined. The present invention is further directed to a continuous process for the preparation of Topiramate.