Inventors:
Peggy Wingard - Houston TX, US
Eric Burak - East Haddam CT, US
Ekaterina Gibiansky - Potomac MD, US
James Vornov - Avenue Baltimore MD, US
International Classification:
A61K031/66
Abstract:
The present invention is directed to pharmaceutical compositions containing water-soluble prodrugs of propofol and methods of administering the prodrug. In one aspect, a method of inducing and/or maintaining a generalized anesthetic state comprises administering by parenteral infusion a prodrug of propofol in an amount sufficient to cause and/or maintain loss of consciousness. In another aspect, a prodrug of propofol is administered for producing a sedated state in a subject.