Inventors:
Paul W. Sanders - Birmingham AL, US
Assignee:
The UAB Research Foundation - Birmingham AL
The United States of America, as Represented by the Department of Veterans Affairs - Washington DC
International Classification:
A61K 39/00, A61K 38/00, A61K 38/10, A61K 38/12, A61K 38/04
US Classification:
4241851, 530317, 530326, 530327
Abstract:
Provided herein are polypeptides comprising or consisting essentially of a QSYDNTLSGSYVF (SEQ ID NO:1) or LSADSSGSYLYVF (SEQ ID NO:2) amino acid sequence. Also provided herein are methods of treating or preventing cast nephropathy in a subject. The methods comprise identifying a subject with or at risk of developing cast nephropathy and administering to the subject any of the polypeptides disclosed herein.