Inventors:
Paul Bollyky - Seattle WA, US
Gerald T. Nepom - Lopez WA, US
Michael G. Kinsella - Seattle WA, US
Assignee:
BENAROYA RESEARCH INSTITUTE AT VIRGINIA MASON - Seattle WA
International Classification:
A61K 39/35, A61P 11/06, A61K 39/36, A61P 11/08, A61P 11/04, A61P 11/00, A61P 37/08
Abstract:
A composition for treating an airway inflammatory disease having high molecular weight, crosslinked hyaluronan and at least one aeroallergen is provided. A method of inducing immune tolerance to one or more aeroallergens in a mammalian subject suffering from or at risk of developing an airway inflammatory disease, and a method of treating a human subject suffering from or at risk of developing an airway inflammatory disease or condition of the lungs are also provided.