Inventors:
Ronald Charles Bernotas - Bridgewater NJ
Paul Wayne Brown - Leawood KS
Gary Thomas Emmons - Washington NJ
Chi-Hsin Richard King - Slingerlands NY
Assignee:
Aventis Pharmaceuticals Inc. - Bridgewater NJ
International Classification:
C07D21122
US Classification:
546240, 546 14, 546225, 546236, 546237, 546238, 546239, 546241
Abstract:
The present invention is directed to sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester, a metabolite of the 5HT antagonist (+)--(2,3-dimethoxyphenyl)- -[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and a processes for its preparation and its use in the treatment for a number of disease states.