PATRICK FLAHERTY
Real Estate Commission in Pittsburgh, PA
License number
Pennsylvania RS335750
Category
Real Estate Commission
Type
Real Estate Salesperson-Standard
Address
Address
Pittsburgh, PA 15220
Personal information
See more information about PATRICK FLAHERTY at radaris.comName
Address
Phone
470 E Street Rd, Warminster, PA 18974
489 Lancer Dr, Columbia, PA 17512
4503 Parade Blvd, Erie, PA 16504
51 Lewis Run Rd, West Mifflin, PA 15122
50 Peninsula Dr, Erie, PA 16505
Professional information
Patrick Flaherty
Location:
Greater Pittsburgh Area
Industry:
Hospital & Health Care
Assistant Professor At Duquense University/Med. Chem
Position:
Associate Professor at Duquense University/Med. Chem
Location:
Greater Pittsburgh Area
Industry:
Pharmaceuticals
Work:
Duquense University/Med. Chem
- Duquense University/Med. Chem since May 2011
-
Associate Professor
Duquesne University
- PIttsburgh, PA Aug 2005 - May 2011
-
Assistant Professor/ Med Chem
Vitae Pharma (formerly Concurrent Pharma)
2002 - 2005
-
senior scientist
vitae pharmaceuticals
2001 - 2005
-
senior scientist
University of Kansas
1995 - 2001
-
Post-doc
Education:
University of Iowa 1987 - 1993
University of Pittsburgh 1984 - 1986
B.S., Chemistry (ACS tract) University of Kansas
University of Pittsburgh 1984 - 1986
B.S., Chemistry (ACS tract) University of Kansas
Diaminoalkane Aspartic Protease Inhibitors
US Patent:
7754737, Jul 13, 2010
Filed:
Oct 7, 2005
Appl. No.:
11/664558
Inventors:
John J. Baldwin - Gwynedd PA, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Maple Glen PA, US
Salvacion Cacatian - Philadelphia PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Elkins Park PA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick T. Flaherty - Pittsburgh PA, US
Jean-Pierre Wery - Indianapolis IN, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Maple Glen PA, US
Salvacion Cacatian - Philadelphia PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Elkins Park PA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick T. Flaherty - Pittsburgh PA, US
Jean-Pierre Wery - Indianapolis IN, US
Assignee:
Vitae Pharmaceuticals, Inc. - Fort Washington PA
International Classification:
C07D 417/04, C07D 409/06, C07D 405/06, C07D 401/06, C07D 417/06, C07D 265/30, C07D 211/22, C07D 211/26, A61K 31/5377, A61K 31/5375, A61K 31/445, A61K 31/4525, A61K 31/453, A61K 31/4535, A61K 31/454, A61K 31/4545
US Classification:
514330, 514331, 514316, 514326, 514320, 514323, 514318, 5142102, 546226, 546232, 546235, 546189, 546209, 546212, 546205, 546194, 546210, 546200, 546199, 544169
Abstract:
Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.
Piperidine Renin Inhibitors
US Patent:
8580823, Nov 12, 2013
Filed:
May 11, 2012
Appl. No.:
13/469562
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Ambler PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville MA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Lanqi Jia - Horsham PA, US
Patrick T. Flaherty - Pittsburgh PA, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Ambler PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville MA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Lanqi Jia - Horsham PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Assignee:
Vitae Pharmaceuticals, Inc. - Fort Washington PA
International Classification:
A61K 31/445
US Classification:
514326, 546207, 546209
Abstract:
The present invention is directed to aspartic protease inhibitors represented by the following structural formula:The present invention is also directed to pharmaceutical compositions comprising the aspartic protease inhibitors of Structural Formula (I). Methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using these aspartic protease inhibitors are also disclosed.
Piperidinyl Carbamate Intermediates For The Synthesis Of Aspartic Protease Inhibitors
US Patent:
8487108, Jul 16, 2013
Filed:
Nov 13, 2006
Appl. No.:
12/084928
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
David A. Claremon - Maple Glen PA, US
Colin Tice - Ambler PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville PA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Wei Zhao - Eagleville PA, US
Patrick T. Flaherty - Pittsburgh PA, US
David A. Claremon - Maple Glen PA, US
Colin Tice - Ambler PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville PA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Wei Zhao - Eagleville PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Assignee:
Vitae Pharmaceuticals, Inc. - Fort Washington PA
International Classification:
C07D 211/22, C07D 211/60
US Classification:
546227, 546232
Abstract:
The present invention is directed to aspartic protease inhibitors. Certain aspartic protease inhibitors of the invention can be represented by the following structural formula or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.
Piperidine Derivatives As Renin Inhibitors
US Patent:
2009031, Dec 24, 2009
Filed:
Sep 17, 2007
Appl. No.:
12/311020
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Amble PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville MA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick T. Flaherty - Pittsburgh PA, US
David A. Claremon - Maple Glen PA, US
Colin M. Tice - Amble PA, US
Salvacion Cacatian - Blue Bell PA, US
Lawrence W. Dillard - Yardley PA, US
Alexey V. Ishchenko - Somerville MA, US
Jing Yuan - Lansdale PA, US
Zhenrong Xu - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Wei Zhao - Eagleville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick T. Flaherty - Pittsburgh PA, US
International Classification:
A61K 31/445, C07D 405/12, C07D 315/00
US Classification:
514326, 546207, 549426
Abstract:
The present invention is directed to aspartic protease inhibitors represented by the following structural formula; or a pharmaceutically acceptable salt thereof. The present invention is also directed to pharmaceutical compositions comprising the aspartic protease inhibitors of Structural Formula (I). Methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using these aspartic protease inhibitors are also disclosed.
Renin Inhibitors
US Patent:
2010017, Jul 15, 2010
Filed:
Apr 4, 2008
Appl. No.:
12/450631
Inventors:
Jonh J. Baldwin - Gwynedd Valley PA, US
Salvacion Cacatian - Blue Bell PA, US
David Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Damiano Ghirlanda - Legnago, IT
Alexey V. Ishchenko - Somerville MA, US
Lara S. Kallander - King of Prussia PA, US
Brian Lawhorn - King of Prussia PA, US
Colin A. Leach - Collegeville PA, US
Qing Lu - King of Prussia PA, US
Gerard McGeehan - Garnet Valley PA, US
Jaclyn R. Patterson - King of Prussia PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick Stoy - King of Prussia PA, US
Lamont R. Terrell - King of Prussia PA, US
Colin Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Catherine C. K. Yuan - King of Prussia PA, US
Jing Zhang - Waltham MA, US
Wei Zhao - Eagleville PA, US
Salvacion Cacatian - Blue Bell PA, US
David Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Damiano Ghirlanda - Legnago, IT
Alexey V. Ishchenko - Somerville MA, US
Lara S. Kallander - King of Prussia PA, US
Brian Lawhorn - King of Prussia PA, US
Colin A. Leach - Collegeville PA, US
Qing Lu - King of Prussia PA, US
Gerard McGeehan - Garnet Valley PA, US
Jaclyn R. Patterson - King of Prussia PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Patrick Stoy - King of Prussia PA, US
Lamont R. Terrell - King of Prussia PA, US
Colin Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Catherine C. K. Yuan - King of Prussia PA, US
Jing Zhang - Waltham MA, US
Wei Zhao - Eagleville PA, US
International Classification:
A61K 31/675, C07D 211/34, A61K 31/445, C07D 265/30, A61K 31/5375, C07D 413/06, A61K 31/5377, A61K 31/535, A61K 31/517, A61K 31/554, A61K 31/4965, A61K 31/5415, A61K 31/55, A61K 31/551, A61K 31/47, A61K 31/566, A61P 25/28, A61P 33/06, A61P 31/18, A61P 9/12, A61P 9/10, A61P 25/22, A61P 27/06
US Classification:
514 91, 546226, 514330, 544162, 5142375, 544131, 5142355, 5142335, 544146, 51425217, 51421107, 51425506, 5142242, 51421207, 514221, 514307, 51421105, 514171
Abstract:
Disclosed are compounds of Formula (I) wherein the R, R, R, R, X, Y, A, Q, E, and G are defined herein. These compounds bind to aspartic proteases to inhibit their activity and are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also disclosed are methods of use of the compounds of Formula I for ameliorating or treating aspartic protease related disorders in a subject in need thereof.
Renin Inhibitors
US Patent:
2010016, Jul 1, 2010
Filed:
Jun 20, 2008
Appl. No.:
12/665222
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
Salvacion Cacatian - Blue Bell PA, US
David A. Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Lanqi Jia - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Colin M. Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Wei Zhao - Eagleville PA, US
Linghang Zhuang - Chalfont PA, US
Jing Zhang - Waltham MA, US
Salvacion Cacatian - Blue Bell PA, US
David A. Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Lanqi Jia - Horsham PA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Colin M. Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Wei Zhao - Eagleville PA, US
Linghang Zhuang - Chalfont PA, US
Jing Zhang - Waltham MA, US
International Classification:
A61K 31/166, C07C 237/24, A61K 31/165, C07C 237/32, A61P 9/00, A61P 7/10, A61P 5/40, A61P 9/12
US Classification:
514620, 564189, 514613, 564164, 564157
Abstract:
The present invention is directed to aspartic protease inhibitors. The present invention is also directed to pharmaceutical compositions comprising the disclosed aspartic protease inhibitors. The present invention is further directed to methods of antagonizing one or more aspartic proteases in a subject in need thereof, and methods for treating an aspartic protease mediated disorder in a subject using the disclosed aspartic protease inhibitors.
Renin Inhibitors
US Patent:
2010016, Jun 24, 2010
Filed:
Jun 20, 2008
Appl. No.:
12/665213
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
Salvacion Cacatian - Blue Bell PA, US
David A. Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Alexey V. Ishchenko - Somerville MA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Colin M. Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing yuan - Lansdale PA, US
Wei Zhao - Eagleville PA, US
Salvacion Cacatian - Blue Bell PA, US
David A. Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Alexey V. Ishchenko - Somerville MA, US
Gerard McGeehan - Garnet Valley PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Colin M. Tice - Ambler PA, US
Zhenrong Xu - Horsham PA, US
Jing yuan - Lansdale PA, US
Wei Zhao - Eagleville PA, US
International Classification:
A61K 31/335, C07D 309/04, C07C 271/10, C07D 313/04, A61K 31/351, A61K 31/24, A61P 9/10
US Classification:
514450, 549426, 560 27, 549346, 514459, 514539
Abstract:
Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.
Renin Inhibitors
US Patent:
2010013, May 27, 2010
Filed:
Apr 4, 2008
Appl. No.:
12/450619
Inventors:
John J. Baldwin - Gwynedd Valley PA, US
Salvacion Cacatian - Blue Bell PA, US
David Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Damiamo Ghirlanda - Legnago, IT
Xiaoping Hou - Pennington NJ, US
Lara S. Kallander - King of Prussia PA, US
Beth A. Knapp-Reed - King of Prussia PA, US
Brian Lawhorn - King of Prussia PA, US
Qing Lu - King of Prussia PA, US
Gerard McGeehan - Garnet Valley PA, US
Simon Semus - Collegeville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Lamont R. Terrell - King of Prussia PA, US
Colin Tice - Ambler PA, US
Tritin Tran - King of Prussia PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Jing Zhang - Waltham MA, US
Wei Zhao - Eagleville PA, US
Salvacion Cacatian - Blue Bell PA, US
David Claremon - Maple Glen PA, US
Lawrence W. Dillard - Yardley PA, US
Patrick T. Flaherty - Pittsburgh PA, US
Damiamo Ghirlanda - Legnago, IT
Xiaoping Hou - Pennington NJ, US
Lara S. Kallander - King of Prussia PA, US
Beth A. Knapp-Reed - King of Prussia PA, US
Brian Lawhorn - King of Prussia PA, US
Qing Lu - King of Prussia PA, US
Gerard McGeehan - Garnet Valley PA, US
Simon Semus - Collegeville PA, US
Robert D. Simpson - Wilmington DE, US
Suresh B. Singh - Kendall Park NJ, US
Lamont R. Terrell - King of Prussia PA, US
Colin Tice - Ambler PA, US
Tritin Tran - King of Prussia PA, US
Zhenrong Xu - Horsham PA, US
Jing Yuan - Lansdale PA, US
Jing Zhang - Waltham MA, US
Wei Zhao - Eagleville PA, US
International Classification:
A61K 31/445, A61K 31/554, A61K 31/55, A61K 31/551, A61K 31/549, A61K 31/5377, A61K 31/5375, A61K 31/4545, C07D 417/12, C07D 265/30, C07D 401/06, C07D 401/10, C07D 211/34, A61P 25/00, A61P 9/12, A61P 9/10
US Classification:
51421107, 51421207, 514221, 5142235, 5142355, 5142362, 5142375, 514316, 514318, 514330, 544133, 544165, 546189, 546194, 546226
Abstract:
Described are compounds which bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.