Inventors:
J. Gregory Reid - Manlius NY
Paul R. Brodfuehrer - Syracuse NY
Patrick R. Smith - Syracuse NY
Assignee:
Briston-Myers Squibb Company - Princeton NY
International Classification:
E07D50128
Abstract:
This invention relates to a method of producing 3-alkanoyloxymethyl-3-cephem-4-carboxylic acids from 3-hydroxymethyl-3-cephem-4-carboxylic acids in an aqueous medium for a practical, large-scale production. Moreover, the invention provides an ideal intermediate for the process.