Inventors:
Patricia Morris - Woodside NY, US
International Classification:
A61K048/00, C07K014/47, C12N015/85
US Classification:
514/008000, 435/455000, 530/359000
Abstract:
Disclosed are compositions and methods for introducing Peptide Nucleic Acids (PNAS) into cell nuclei. The PNAs are linked to a ligand that binds a nuclear receptor. The methods have therapeutic and diagnostic applications.