MR. PARVIZ LALEZARI, M.D.
Osteopathic Medicine in Scarsdale, NY
License number
New York 096553-1
Category
Osteopathic Medicine
Type
Internal Medicine
License number
New York 096553-1
Category
Osteopathic Medicine
Type
Hematology
Address
Address
One Church Ln, Scarsdale, NY 10583
Phone
(914) 723-3875
(718) 653-3284 (Fax)
(718) 653-3284 (Fax)
Personal information
See more information about PARVIZ LALEZARI at radaris.comName
Address
Phone
1 Church Ln, Scarsdale, NY 10583
1390 Demarest Rd, Orient, NY 11957
1 Church Ln, Scarsdale, NY 10583
1 Church Ln, Scarsdale, NY 10583
Professional information
Method Of Treating Hyperlipidemia With Granulocyte Colony Stimulating Factor
US Patent:
5385731, Jan 31, 1995
Filed:
Nov 14, 1991
Appl. No.:
7/795929
Inventors:
Parviz Lalezari - Scarsdale NY
Manouchehr Khorshidi - Great Neck NY
Manouchehr Khorshidi - Great Neck NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
A61K 3702
US Classification:
424 851
Abstract:
A novel method for the treatment of hyperlipidemia/high serum cholesterol is disclosed which is based on the parenteral administration of granulocyte colony stimulating factor.
Compound, Composition And Method For The Reduction Of Lipids The Modification Of The Affinity Of Hemoblogin For Oxygen And The Prevention Of Platelet Aggregation
US Patent:
5268500, Dec 7, 1993
Filed:
Oct 18, 1991
Appl. No.:
7/778706
Inventors:
Iraj Lalezari - Scarsdale NY
Samuel Rahbar - Encino CA
Parviz Lalezari - Scarsdale NY
Samuel Rahbar - Encino CA
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
City of Hope - Duarte CA
City of Hope - Duarte CA
International Classification:
A61K 31195, C07C22900
US Classification:
560 34
Abstract:
Novel compounds are disclosed which have the formula: ##STR1## wherein R. sub. 1, R. sub. 2, R. sub. 3 and R. sub. 4 may be the same or different and independently selected from the group consisting of hydrogen, halogen, straight and branched chain alkyl of from 1-6 carbon atoms, aryl, cycloalkyl of 4 to 7 carbon atoms; and alkoxy of 1 to 6 carbon atoms; R. sub. 5 and R. sub. 6 may be the same or different and are selected from the group consisting of hydrogen, halogen, straight and branched chain alkyl groups of from 1-6 carbon atoms, aralkyl groups wherein the alkyl portion has from 1-6 carbon atoms cycloalkyl of from 4-7 carbon atoms and aryl; R. sub. 7 is hydrogen or a straight or branched chain alkyl group of 1-6 carbon atoms and the pharmaceutically acceptable salts thereof.
These compounds are useful for the treatment of hyperlipidemia and for the in vivo and in vitro treatment of hemoglobin or blood to modify the affinity of hemoglobin for oxygen.
Process And Reagents For Antibody Detection Involving Erythrocyte Agglutination
US Patent:
4436825, Mar 13, 1984
Filed:
May 21, 1982
Appl. No.:
6/380939
Inventors:
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Hospital and Medical Center, Inc. - Bronx NY
International Classification:
G01N 3354
US Classification:
436520
Abstract:
A process for the detection of antibodies in a test sample is described. This process involves:
(a) preparing an essentially isotonic and low ionic strength suspension comprising said sample and erythrocytes in net negatively-charged form;
(b) maintaining said suspension for at least 30 seconds;
(c) combining said suspension with an amount of a solution of polymer effective for agglutination of said erythrocytes;
(d) separating the resultant agglutinates of polymer and erythrocytes from supernatant of said suspension;
(e) dispersing said agglutinates in a hypertonic salt solution having an essentially neutral pH; and
(f) monitoring the dispersed agglutinates for dissociation of erythrocytes.
This process permits rapid detection of antibodies with great ease. Their presence is indicated by persistence of the agglutinates in the dispersion.
Method Of Synthesis And Novel Compounds For Pharmaceutical Uses
US Patent:
5093367, Mar 3, 1992
Filed:
Feb 7, 1990
Appl. No.:
7/477048
Inventors:
Iraj Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
A61K 31195
US Classification:
514564
Abstract:
The present invention is concerned with a process for the synthesis of substituted arylureidophenexymethyl propionic acids and an analogous benzamides series of compounds which have activity in the dissociation of oxygen from hemoglobin. In addition the process may be utilized to prepare compounds which are known.
Modified Hemoglobin And Its Use As A Component Of An Artificial Blood Substitute
US Patent:
5962651, Oct 5, 1999
Filed:
Jul 31, 1997
Appl. No.:
8/903930
Inventors:
Iraj Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
A61K 3514, A61K 3816, C07C 6976
US Classification:
530385
Abstract:
The present invention provides a chemically modified form of hemoglobin that is stabilized and can efficiently bind and release oxygen. In addition the chemically modified hemoglobin may be polymerized to increase its molecular weight and increase its stability so that it will have a longer half life in the circulatory system and may be used as a stable oxygen transport mediator which is useful as the basis of a blood substitute.
Method Of Synthesis And Novel Compounds For Pharmaceutical Uses
US Patent:
5292935, Mar 8, 1994
Filed:
Jan 15, 1992
Appl. No.:
7/821409
Inventors:
Iraj Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
C07C27318
US Classification:
562439
Abstract:
The present invention is concerned with a process for the synthesis of substituted arylureidophenoxymethyl propionic acids and an analogous benzamides series of compounds which have activity in the dissociation of oxygen from hemoglobin. In addition the process may be utilized to prepare compounds which are known.
Method Of Synthesis And Novel Compounds For Pharmaceutical Uses
US Patent:
4921997, May 1, 1990
Filed:
Jun 15, 1988
Appl. No.:
7/207098
Inventors:
Iraj Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
C07C12719
US Classification:
560 34
Abstract:
The present invention is concerned with a process for the synthesis of substituted arylureidophenexymethyl propionic acids and an analogous benzamides series of compounds which have activity in the dissociation of oxygen from hemoglobin. In addition, the process may be utilized to prepare compounds which are known.
Method Of Synthesis And Novel Compounds For Pharmaceutical Uses
US Patent:
5472981, Dec 5, 1995
Filed:
Nov 29, 1993
Appl. No.:
8/158702
Inventors:
Iraj Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Parviz Lalezari - Scarsdale NY
Assignee:
Montefiore Medical Center - Bronx NY
International Classification:
A61K 31195, A61K 3124
US Classification:
514564
Abstract:
The present invention is concerned with a method for treating hemoglobin or blood in vivo or in vitro to modify the affinity of hemoglobin for oxygen, said method comprising causing an effective amount of a substituted arylureidophenoxymethyl propionic acid to come in contact with hemoglobin.
Method Of Detecting Red Cell Antigen-Antibody Reactions
US Patent:
7919266, Apr 5, 2011
Filed:
Apr 23, 2008
Appl. No.:
12/148946
Inventors:
Parviz Lalezari - Scarsdale NY, US
Assignee:
Clavina Diagnostics, Inc. - Longwood FL
International Classification:
G01N 33/00, G01N 31/00, G01N 33/539
US Classification:
435 725, 435 2, 4352872, 436506, 436507, 436513, 436518, 436520, 436538, 436539, 436 17, 436 18, 436165, 436166, 436175, 436177, 436178, 436179
Abstract:
A process for the detection of antibodies in a test sample by preparing a suspension of erythrocytes with a test serum or plasma by mixing a test serum or plasma with erythrocytes; incubating the suspension of erythrocytes at a temperature of from 37° C. to 45° C. to bind any antibodies in the test serum or plasma to the surface of said erythrocytes; combining the suspension of erythrocytes with an amount of a solution of a macromolecule which is effective to agglutinate the erythrocytes; packing the resultant red cell agglutinates by centrifuging the suspension of erythrocytes; and, determining the presence of anti-erythrocyte antibodies by observing if antibody-dependent erythrocyte agglutination has occurred.
Method Of Detecting Red Cell Antigen-Antibody Reactions
US Patent:
2008026, Oct 23, 2008
Filed:
Apr 3, 2008
Appl. No.:
12/080507
Inventors:
Parviz Lalezari - Scarsdale NY, US
International Classification:
G01N 33/569
US Classification:
435 725
Abstract:
A process for the detection of antibodies in a test sample by carrying out the following steps: